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Table 3

Association between ADPRT genotype and CaP risk

SubjectsGenotypeP value*VA versus VVAA versus VV
VVVAAACrude OR (95%CI)Adjusted OR (95% CI)Crude OR (95% CI)Adjusted OR (95% CI)
Caucasians         
 Total controls 313 107  1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 
 Total cases 306 113 19 0.02 1.08 (0.59–1.96) 1.18 (0.85–1.64) 2.78 (0.68–11.41) 2.65 (1.08–6.49) 
<65 years         
 Controls 151 48  1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 
 Cases 144 41 11 0.03 0.90 (0.36–2.23) 1.11 (0.67–1.83) 5.77 (0.58–57.51)§ 4.77 (1.01–22.44)  
≥65 years         
 Controls 162 59  1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 
 Cases 162 72 0.49 1.22 (0.55–2.70) 1.21 (0.78–1.87) 1.60 (0.24–10.46) 1.78 (0.55–5.82) 
African Americans         
 Total controls 88  1.00 (Ref.) 1.00 (Ref.)   
 Total cases 45 0.88 1.09 (0.14–8.28) 0.98 (0.24–3.99) NA NA 
<65 years         
 Controls 63      
 Cases 30 0.93 NA NA NA NA 
≥65 years         
 Controls 25      
 Cases 15 0.80 NA NA NA NA 
SubjectsGenotypeP value*VA versus VVAA versus VV
VVVAAACrude OR (95%CI)Adjusted OR (95% CI)Crude OR (95% CI)Adjusted OR (95% CI)
Caucasians         
 Total controls 313 107  1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 
 Total cases 306 113 19 0.02 1.08 (0.59–1.96) 1.18 (0.85–1.64) 2.78 (0.68–11.41) 2.65 (1.08–6.49) 
<65 years         
 Controls 151 48  1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 
 Cases 144 41 11 0.03 0.90 (0.36–2.23) 1.11 (0.67–1.83) 5.77 (0.58–57.51)§ 4.77 (1.01–22.44)  
≥65 years         
 Controls 162 59  1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 
 Cases 162 72 0.49 1.22 (0.55–2.70) 1.21 (0.78–1.87) 1.60 (0.24–10.46) 1.78 (0.55–5.82) 
African Americans         
 Total controls 88  1.00 (Ref.) 1.00 (Ref.)   
 Total cases 45 0.88 1.09 (0.14–8.28) 0.98 (0.24–3.99) NA NA 
<65 years         
 Controls 63      
 Cases 30 0.93 NA NA NA NA 
≥65 years         
 Controls 25      
 Cases 15 0.80 NA NA NA NA 
*

P value, Fisher’s exact or χ2 test.

OR adjusted for age, BPH, and FH.

Referent.

§

An expected cell value is less than five; Fisher’s exact or χ2 test results should be considered.

Not applicable.

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