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Table 1

Genotypes for common human prostate cancer cell lines

Cell lineTissue of originAndrogen- dependentNFκBa constitutive activationGenotype
Rbp53PTEN
LNCaP Lymph node Yes Yes +/+ +/+ −/− 
PC-3 Bone marrow No Yes −/− −/− −/− 
DU145 Brain tumor No Yes +/+ −/− +/+ 
Cell lineTissue of originAndrogen- dependentNFκBa constitutive activationGenotype
Rbp53PTEN
LNCaP Lymph node Yes Yes +/+ +/+ −/− 
PC-3 Bone marrow No Yes −/− −/− −/− 
DU145 Brain tumor No Yes +/+ −/− +/+ 
a

NFκB, nuclear factor κB.

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