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Table 2

Clinical and pathological characteristics of adenomas from patients used in this study

Sex, age of patient, and a brief description of tumor type are given.

Patient IDSex, ageClinical features/tumor sizeIHC
93 M, 57 NF, visual loss, cavernous sinus invasion, 1.5 cm Neg.a 
74 M, 67 NF, hypogonadism, 2.5 cm Neg. 
164 M, 35 NF, visual loss, 4 cm Neg. 
153 M, 72 NF, hypogonadism, 2 cm Neg. 
155 M, 66 NF, headache, visual loss, hypocortisolism, 1.5 cm Neg. 
104 F, 61 NF, visual loss, 1.5 cm Neg. 
105 F, 48 NF Neg. 
75 M, 60 NF, visual loss, 2 cm Neg. 
68 M, 74 NF Neg. 
191 F, 44 NF Neg. 
65 F, 54 NF FSH 1+, LH 2+ 
77 M, 67 NF FSH 2+ 
174 F, 53 NF FSH 1+, LH 1+ 
143 M, 60 NF FSH 1+, LH 1+, ACTH 1+ 
89 M, 62 NF FSH 2+ 
91 M, 56 NF FSH 2+, TSH 1+ 
100 F, 65 NF FSH 1+, LH 1+, ACTH 2+, PRL+, GH1+ 
112 F, 58 NF FSH 3+, PRL 2+, LH 2+ 
69 M, 67 NF FSH 2+, LH 3+ 
60 F, 90 NF FSH 1+, LH 2-3+ 
198 M, 58 NF FSH 1+, LH 1+ 
208 F, 47 NF LH1+ 
138 M, 60 NF FSH 1-2+, LH 1-2+ 
183 M, 36 Hyperprolactinemia, visual loss, 2 cm PRL 3+ 
192 M, 41 Hyperprolactinemia, visual loss, 3 cm PRL 3+ 
151 M, 52 Hyperprolactinemia PRL 3+, GH 1+ 
240 M, 39 Hyperprolactinemia PRL 3+ 
244 F, 40 Hyperprolactinemia PRL 3+ 
213 M, 24 Hyperprolactinemia PRL 3+ 
123 M, 30 Acromegaly, 2 cm GH 3+, TSH 3+, FSH 3+, LH 3+ 
196 F, 69 Acromegaly, 2 cm NDb 
168 F, 39 Acromegaly, 1 cm GH 3+, PRL 2-3+ 
218 F, 33 Acromegaly GH 3+, PRL 2-3+ 
145 M, 34 Acromegaly GH 3+, PRL 2-3+, TSH 1+ 
232 F, 39 Cushing’s disease ACTH 2+ 
137 F, 41 Cushing’s disease ND 
239 F, 55 Cushing’s disease, cav sinus invasion ACTH 4+ 
126 F, 29 Cushing’s disease, 1.6 cm ACTH 3+ 
233 M, 11 Cushing’s disease ACTH 3+, FSH 1+ 
Patient IDSex, ageClinical features/tumor sizeIHC
93 M, 57 NF, visual loss, cavernous sinus invasion, 1.5 cm Neg.a 
74 M, 67 NF, hypogonadism, 2.5 cm Neg. 
164 M, 35 NF, visual loss, 4 cm Neg. 
153 M, 72 NF, hypogonadism, 2 cm Neg. 
155 M, 66 NF, headache, visual loss, hypocortisolism, 1.5 cm Neg. 
104 F, 61 NF, visual loss, 1.5 cm Neg. 
105 F, 48 NF Neg. 
75 M, 60 NF, visual loss, 2 cm Neg. 
68 M, 74 NF Neg. 
191 F, 44 NF Neg. 
65 F, 54 NF FSH 1+, LH 2+ 
77 M, 67 NF FSH 2+ 
174 F, 53 NF FSH 1+, LH 1+ 
143 M, 60 NF FSH 1+, LH 1+, ACTH 1+ 
89 M, 62 NF FSH 2+ 
91 M, 56 NF FSH 2+, TSH 1+ 
100 F, 65 NF FSH 1+, LH 1+, ACTH 2+, PRL+, GH1+ 
112 F, 58 NF FSH 3+, PRL 2+, LH 2+ 
69 M, 67 NF FSH 2+, LH 3+ 
60 F, 90 NF FSH 1+, LH 2-3+ 
198 M, 58 NF FSH 1+, LH 1+ 
208 F, 47 NF LH1+ 
138 M, 60 NF FSH 1-2+, LH 1-2+ 
183 M, 36 Hyperprolactinemia, visual loss, 2 cm PRL 3+ 
192 M, 41 Hyperprolactinemia, visual loss, 3 cm PRL 3+ 
151 M, 52 Hyperprolactinemia PRL 3+, GH 1+ 
240 M, 39 Hyperprolactinemia PRL 3+ 
244 F, 40 Hyperprolactinemia PRL 3+ 
213 M, 24 Hyperprolactinemia PRL 3+ 
123 M, 30 Acromegaly, 2 cm GH 3+, TSH 3+, FSH 3+, LH 3+ 
196 F, 69 Acromegaly, 2 cm NDb 
168 F, 39 Acromegaly, 1 cm GH 3+, PRL 2-3+ 
218 F, 33 Acromegaly GH 3+, PRL 2-3+ 
145 M, 34 Acromegaly GH 3+, PRL 2-3+, TSH 1+ 
232 F, 39 Cushing’s disease ACTH 2+ 
137 F, 41 Cushing’s disease ND 
239 F, 55 Cushing’s disease, cav sinus invasion ACTH 4+ 
126 F, 29 Cushing’s disease, 1.6 cm ACTH 3+ 
233 M, 11 Cushing’s disease ACTH 3+, FSH 1+ 
a

Neg., immunostaining for GH, ACTH, PRL, FSH, LH, and TSH were negative.

b

ND, not determined.

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