American Association for Cancer Research

Table 3

Overlapping of BRAF mutation with other genetic alterations in PTC

BRAF mutation	No. of tumors	RET/PTC positive	NRAS mutation^a
Yes	21	8 (38%)	0 (0%)
No	35	13 (37%)	ND^b
Total	56	21 (38%)	ND^b

Exons 1 and 2 of the NRAS gene were PCR amplified individually and sequenced to detect NRAS mutation at codons 12, 13, and 61.

ND, not done.