American Association for Cancer Research

Table 1

BRAF gene mutation in a panel of thyroid tumor cell lines

Cell line	Tumor type	Passages	Metastasis	BRAF mutation
KAK-1	FTA	50	No	Yes
KAT-4	ATC^a	16	Yes	Yes
KAT-18	ATC	35	Yes	No
SW1736	ATC	>9	Yes	Yes
ARO81	ATC	65	Yes	Yes^b
DRO90	ATC	35	Yes	Yes^b
MRO87	FTC	46	Unknown	Yes
WRO82	FTC	67	Yes	No
KAT-10	PTC	36	Yes	Yes
NPA87	PTC	44	Unknown	Yes

Cell line	Tumor type	Passages	Metastasis	BRAF mutation
KAK-1	FTA	50	No	Yes
KAT-4	ATC^a	16	Yes	Yes
KAT-18	ATC	35	Yes	No
SW1736	ATC	>9	Yes	Yes
ARO81	ATC	65	Yes	Yes^b
DRO90	ATC	35	Yes	Yes^b
MRO87	FTC	46	Unknown	Yes
WRO82	FTC	67	Yes	No
KAT-10	PTC	36	Yes	Yes
NPA87	PTC	44	Unknown	Yes

ATC, anaplastic thyroid carcinoma; FTC, follicular thyroid carcinoma; NPA87, a poorly differentiated PTC cell line.

Homozygous/hemizygous BRAF mutation.