American Association for Cancer Research

Table 1

Detoxification polymorphisms examined in human study, including 231 cases and 256 controls

Locus	No. of genotypes	χ²	P
EPHX1-exon3(1)^a	3	5.61	0.06
EPHX1-exon3(2)^b	3	1.99	0.37
EPHX1-exon3(3)^c	6	11.3	0.046
EPHX1-exon4	3	1.24	0.53
EPHX2	3	10.2	0.02
GSTM1	4	1.16	0.76
GSTM2	2	2.3	0.12
GSTM3^d	1
GSTP1	59	68.0	0.17
GST12	3	0.68	0.71
GSTA1	3	2.8	0.09
GSTA4	3	1.14	0.56
GSTT1	4	0.66	0.88
GSTT2	3	1.5	0.46

Locus	No. of genotypes	χ²	P
EPHX1-exon3(1)^a	3	5.61	0.06
EPHX1-exon3(2)^b	3	1.99	0.37
EPHX1-exon3(3)^c	6	11.3	0.046
EPHX1-exon4	3	1.24	0.53
EPHX2	3	10.2	0.02
GSTM1	4	1.16	0.76
GSTM2	2	2.3	0.12
GSTM3^d	1
GSTP1	59	68.0	0.17
GST12	3	0.68	0.71
GSTA1	3	2.8	0.09
GSTA4	3	1.14	0.56
GSTT1	4	0.66	0.88
GSTT2	3	1.5	0.46

EPHX1-exon3(1) is the Tyr¹¹³His polymorphism alone.

EPHX1-exon3(2) is the A/G polymorphism at bp 17,693 alone.

EPHX1-exon3(3) is both exon 3 polymorphisms together.

GSTM3 was monomorphic.