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Table 1

Detoxification polymorphisms examined in human study, including 231 cases and 256 controls

LocusNo. of genotypesχ2P
EPHX1-exon3(1)a 5.61 0.06 
EPHX1-exon3(2)b 1.99 0.37 
EPHX1-exon3(3)c 11.3 0.046 
EPHX1-exon4 1.24 0.53 
EPHX2 10.2 0.02 
GSTM1 1.16 0.76 
GSTM2 2.3 0.12 
GSTM3d   
GSTP1 59 68.0 0.17 
GST12 0.68 0.71 
GSTA1 2.8 0.09 
GSTA4 1.14 0.56 
GSTT1 0.66 0.88 
GSTT2 1.5 0.46 
LocusNo. of genotypesχ2P
EPHX1-exon3(1)a 5.61 0.06 
EPHX1-exon3(2)b 1.99 0.37 
EPHX1-exon3(3)c 11.3 0.046 
EPHX1-exon4 1.24 0.53 
EPHX2 10.2 0.02 
GSTM1 1.16 0.76 
GSTM2 2.3 0.12 
GSTM3d   
GSTP1 59 68.0 0.17 
GST12 0.68 0.71 
GSTA1 2.8 0.09 
GSTA4 1.14 0.56 
GSTT1 0.66 0.88 
GSTT2 1.5 0.46 
a

EPHX1-exon3(1) is the Tyr113His polymorphism alone.

b

EPHX1-exon3(2) is the A/G polymorphism at bp 17,693 alone.

c

EPHX1-exon3(3) is both exon 3 polymorphisms together.

d

GSTM3 was monomorphic.

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