BRAF mutant-specific genesa,b
| Probe set . | Description . | Fold changec . | Mean changed . | Rank . |
|---|---|---|---|---|
| 40406_at | Macrophage stimulating, pseudogene 9 | 5.7 (4.0–8.5) | 101 | 1 |
| 32115_r_at | Adenosine A2a receptor | 4.2 (1.6–7.5) | 169 | 2 |
| 1047_s_at | Human hepatocyte growth factor-like protein gene | 3.6 (2.4–5.3) | 246 | 3 |
| 40237_at | Tumor-suppressing subtransferable candidate 3 | 3.5 (1.7–5.9) | 108 | 4 |
| 34094_i_at | Human immunoglobulin heavy chain variable region | 3.3 (2.3–5.9) | 510 | 5 |
| 37473_at | Keratin 16 | 3.1 (2.1–6.2) | 179 | 6 |
| 34095_f_at | Human immunoglobulin heavy chain variable region | 2.8 (2.0–4.0) | 1041 | 7 |
| 35350_at | B-cell RAG-associated protein | 2.3 (1.8–3.0) | 162 | 8 |
| 40928_at | SOCS box-containing WD protein SWiP-1 | 2.3 (1.5–3.2) | 705 | 9 |
| 2017_s_at | Cyclin D1 | 2.2 (1.5–3.0) | 243 | 10 |
| 38028_at | Neuronal specific transcription factor DAT1 | 2.2 (1.8–2.8) | 160 | 11 |
| 35566_f_at | Immunoglobulin heavy constant mu | 2.1 (1.5–2.8) | 1419 | 12 |
| 31888_s_at | Tumor-suppressing subtransferable candidate 3 | 2.1 (1.5–2.7) | 324 | 13 |
| 37323_r_at | Hydroxyprostaglandin dehydrogenase 15-(NAD) | 2.1 (1.3–2.9) | 180 | 14 |
| 40317_at | Amiloride-sensitive cation channel 1 | 2.0 (1.8–2.3) | 117 | 15 |
| 32919_at | Homo sapiens, clone IMAGE:3625286 | 2.0 (1.8–2.4) | 184 | 16 |
| Probe set . | Description . | Fold changec . | Mean changed . | Rank . |
|---|---|---|---|---|
| 40406_at | Macrophage stimulating, pseudogene 9 | 5.7 (4.0–8.5) | 101 | 1 |
| 32115_r_at | Adenosine A2a receptor | 4.2 (1.6–7.5) | 169 | 2 |
| 1047_s_at | Human hepatocyte growth factor-like protein gene | 3.6 (2.4–5.3) | 246 | 3 |
| 40237_at | Tumor-suppressing subtransferable candidate 3 | 3.5 (1.7–5.9) | 108 | 4 |
| 34094_i_at | Human immunoglobulin heavy chain variable region | 3.3 (2.3–5.9) | 510 | 5 |
| 37473_at | Keratin 16 | 3.1 (2.1–6.2) | 179 | 6 |
| 34095_f_at | Human immunoglobulin heavy chain variable region | 2.8 (2.0–4.0) | 1041 | 7 |
| 35350_at | B-cell RAG-associated protein | 2.3 (1.8–3.0) | 162 | 8 |
| 40928_at | SOCS box-containing WD protein SWiP-1 | 2.3 (1.5–3.2) | 705 | 9 |
| 2017_s_at | Cyclin D1 | 2.2 (1.5–3.0) | 243 | 10 |
| 38028_at | Neuronal specific transcription factor DAT1 | 2.2 (1.8–2.8) | 160 | 11 |
| 35566_f_at | Immunoglobulin heavy constant mu | 2.1 (1.5–2.8) | 1419 | 12 |
| 31888_s_at | Tumor-suppressing subtransferable candidate 3 | 2.1 (1.5–2.7) | 324 | 13 |
| 37323_r_at | Hydroxyprostaglandin dehydrogenase 15-(NAD) | 2.1 (1.3–2.9) | 180 | 14 |
| 40317_at | Amiloride-sensitive cation channel 1 | 2.0 (1.8–2.3) | 117 | 15 |
| 32919_at | Homo sapiens, clone IMAGE:3625286 | 2.0 (1.8–2.4) | 184 | 16 |
Comparison between 2 BRAF mutants and 57 WT (KRAS and BRAF).
Genes were chosen by D-chip software (see “Materials and Methods”).
Fold change (increase in BRAF mutants) with 90% lower and upper confidence bounds in parentheses.
Difference between means of groups in normalized Affymetrix arbitrary expression values.