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Table 2

BRAF mutant-specific genesa,b

Probe setDescriptionFold changecMean changedRank
40406_at Macrophage stimulating, pseudogene 9 5.7 (4.0–8.5) 101 
32115_r_at Adenosine A2a receptor 4.2 (1.6–7.5) 169 
1047_s_at Human hepatocyte growth factor-like protein gene 3.6 (2.4–5.3) 246 
40237_at Tumor-suppressing subtransferable candidate 3 3.5 (1.7–5.9) 108 
34094_i_at Human immunoglobulin heavy chain variable region 3.3 (2.3–5.9) 510 
37473_at Keratin 16 3.1 (2.1–6.2) 179 
34095_f_at Human immunoglobulin heavy chain variable region 2.8 (2.0–4.0) 1041 
35350_at B-cell RAG-associated protein 2.3 (1.8–3.0) 162 
40928_at SOCS box-containing WD protein SWiP-1 2.3 (1.5–3.2) 705 
2017_s_at Cyclin D1 2.2 (1.5–3.0) 243 10 
38028_at Neuronal specific transcription factor DAT1 2.2 (1.8–2.8) 160 11 
35566_f_at Immunoglobulin heavy constant mu 2.1 (1.5–2.8) 1419 12 
31888_s_at Tumor-suppressing subtransferable candidate 3 2.1 (1.5–2.7) 324 13 
37323_r_at Hydroxyprostaglandin dehydrogenase 15-(NAD) 2.1 (1.3–2.9) 180 14 
40317_at Amiloride-sensitive cation channel 1 2.0 (1.8–2.3) 117 15 
32919_at Homo sapiens, clone IMAGE:3625286 2.0 (1.8–2.4) 184 16 
Probe setDescriptionFold changecMean changedRank
40406_at Macrophage stimulating, pseudogene 9 5.7 (4.0–8.5) 101 
32115_r_at Adenosine A2a receptor 4.2 (1.6–7.5) 169 
1047_s_at Human hepatocyte growth factor-like protein gene 3.6 (2.4–5.3) 246 
40237_at Tumor-suppressing subtransferable candidate 3 3.5 (1.7–5.9) 108 
34094_i_at Human immunoglobulin heavy chain variable region 3.3 (2.3–5.9) 510 
37473_at Keratin 16 3.1 (2.1–6.2) 179 
34095_f_at Human immunoglobulin heavy chain variable region 2.8 (2.0–4.0) 1041 
35350_at B-cell RAG-associated protein 2.3 (1.8–3.0) 162 
40928_at SOCS box-containing WD protein SWiP-1 2.3 (1.5–3.2) 705 
2017_s_at Cyclin D1 2.2 (1.5–3.0) 243 10 
38028_at Neuronal specific transcription factor DAT1 2.2 (1.8–2.8) 160 11 
35566_f_at Immunoglobulin heavy constant mu 2.1 (1.5–2.8) 1419 12 
31888_s_at Tumor-suppressing subtransferable candidate 3 2.1 (1.5–2.7) 324 13 
37323_r_at Hydroxyprostaglandin dehydrogenase 15-(NAD) 2.1 (1.3–2.9) 180 14 
40317_at Amiloride-sensitive cation channel 1 2.0 (1.8–2.3) 117 15 
32919_at Homo sapiens, clone IMAGE:3625286 2.0 (1.8–2.4) 184 16 
a

Comparison between 2 BRAF mutants and 57 WT (KRAS and BRAF).

b

Genes were chosen by D-chip software (see “Materials and Methods”).

c

Fold change (increase in BRAF mutants) with 90% lower and upper confidence bounds in parentheses.

d

Difference between means of groups in normalized Affymetrix arbitrary expression values.

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