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Table 2

Allelic loss in leukoplakia that developed into SOM compared to that which did not

SOM (%) (n = 36)Non-SOM (%) (n = 32)P
No. with LOHa35 (97)15 (47)0.0001
>1 arm lost 26 (72) 9 (28) 0.0006 
LOH on 3p 22/35 (63)b 3/32 (9)b 0.0001 
LOH on 9p 28/36 (78) 9/32 (28) 0.0001 
LOH on 4q 12/30 (39) 1/26 (4) 0.0014 
LOH on 8p 13/36 (36) 6/32 (19) 0.18 
LOH on 11q 6/32 (19) 1/31 (3) 0.10 
LOH on 13q 4/32 (13) 2/30 (7) 0.67 
LOH on 17p 13/36 (36) 9/32 (28) 0.61 
LOH on 3p and/or 9p (but no other arms) 11/36 (31) 3/32 (9) 0.039 
LOH on 3p and/or 9p (plus LOH at any other arm) 24/36 (67) 7/32 (22) 0.0003 
All cases with LOH on 3p and/or 9p 35/36 (97) 10/32 (31) 0.0001 
SOM (%) (n = 36)Non-SOM (%) (n = 32)P
No. with LOHa35 (97)15 (47)0.0001
>1 arm lost 26 (72) 9 (28) 0.0006 
LOH on 3p 22/35 (63)b 3/32 (9)b 0.0001 
LOH on 9p 28/36 (78) 9/32 (28) 0.0001 
LOH on 4q 12/30 (39) 1/26 (4) 0.0014 
LOH on 8p 13/36 (36) 6/32 (19) 0.18 
LOH on 11q 6/32 (19) 1/31 (3) 0.10 
LOH on 13q 4/32 (13) 2/30 (7) 0.67 
LOH on 17p 13/36 (36) 9/32 (28) 0.61 
LOH on 3p and/or 9p (but no other arms) 11/36 (31) 3/32 (9) 0.039 
LOH on 3p and/or 9p (plus LOH at any other arm) 24/36 (67) 7/32 (22) 0.0003 
All cases with LOH on 3p and/or 9p 35/36 (97) 10/32 (31) 0.0001 
a

A total of seven chromosomal arms were tested. Values in parentheses are percentages.

b

Loss/informative cases (% loss).

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