Skip to Main Content
Table 2

Summary of the associations between clinical markers and mdm2 expression

Clinical markermdm2 mRNA expression
No. total patientsConsidering 1526 bp to be “normal” expressionConsidering 1526 and 653 bp to be “normal” expression
No. abnormal patientsPNo. abnormal patientsP
p53 mutation   0.0003  0.02 
 Negative 29   
 Positive   
p53 IHCb   0.023  0.624 
 Negative 12   
 Positive 19   
 NAa     
PR   0.036  0.030 
 Negative 22 11   
 Positive 16   
ER   0.087  0.395 
 Negative 18   
 Positive 20   
HER2/neu oncoprotein   0.228  0.827 
 Low 24 10   
 Medium   
 High   
EGFR   0.434  0.300 
 Negative 23   
 Positive 11   
 NAa     
DNA ploidy   1.000  0.643 
 Euploid 12   
 Aneuploid 26   
G2M phase   0.578  0.115 
 10% 20   
 >11%   
 NAa 14     
P1      
 Negative 0.106 0.546 
 Positive 31   
P2 (150 bp)      
 Negative 18 1.000 1.000 
 Positive 17   
Clinical markermdm2 mRNA expression
No. total patientsConsidering 1526 bp to be “normal” expressionConsidering 1526 and 653 bp to be “normal” expression
No. abnormal patientsPNo. abnormal patientsP
p53 mutation   0.0003  0.02 
 Negative 29   
 Positive   
p53 IHCb   0.023  0.624 
 Negative 12   
 Positive 19   
 NAa     
PR   0.036  0.030 
 Negative 22 11   
 Positive 16   
ER   0.087  0.395 
 Negative 18   
 Positive 20   
HER2/neu oncoprotein   0.228  0.827 
 Low 24 10   
 Medium   
 High   
EGFR   0.434  0.300 
 Negative 23   
 Positive 11   
 NAa     
DNA ploidy   1.000  0.643 
 Euploid 12   
 Aneuploid 26   
G2M phase   0.578  0.115 
 10% 20   
 >11%   
 NAa 14     
P1      
 Negative 0.106 0.546 
 Positive 31   
P2 (150 bp)      
 Negative 18 1.000 1.000 
 Positive 17   
a

NA, tissue not available for analysis.

b

IHC, immunohistochemistry.

Close Modal

or Create an Account

Close Modal
Close Modal