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Table 1

FHIT status and clinicopathological characteristics of tongue SCC tumor samples from 41 patients

TotalFhit negativeFhit positiveP
Total no. of patients 41 28 (68%) 13 (32%)  
Age Mean 56.2 years    
≤50 14 9 (64%) 5 (36%) 0.691 
>50 27 19 (70%) 8 (30%)  
Sex     
Men 26 17 (65%) 9 (35%) 0.734 
Women 15 11 (73%) 4 (27%)  
Histological gradea     
22 12 (54%) 10 (46%) 0.090 
≥2 18 15 (83%) 3 (17%)  
Nodal statusb     
NO 20 14 (70%) 6 (30%) 0.736 
N1–3 20 13 (65%) 7 (35%)  
Stage     
II 15 11 (73%) 4 (27%) 0.734 
III and IV 26 17 (65%) 9 (35%)  
Metastases or recurrence 11 10 (91%) 1 (9%)   
Death 18 15 (83%) 3 (17%)  
Cancer-related death 11 10 (91%) 1 (9%)   
TotalFhit negativeFhit positiveP
Total no. of patients 41 28 (68%) 13 (32%)  
Age Mean 56.2 years    
≤50 14 9 (64%) 5 (36%) 0.691 
>50 27 19 (70%) 8 (30%)  
Sex     
Men 26 17 (65%) 9 (35%) 0.734 
Women 15 11 (73%) 4 (27%)  
Histological gradea     
22 12 (54%) 10 (46%) 0.090 
≥2 18 15 (83%) 3 (17%)  
Nodal statusb     
NO 20 14 (70%) 6 (30%) 0.736 
N1–3 20 13 (65%) 7 (35%)  
Stage     
II 15 11 (73%) 4 (27%) 0.734 
III and IV 26 17 (65%) 9 (35%)  
Metastases or recurrence 11 10 (91%) 1 (9%)   
Death 18 15 (83%) 3 (17%)  
Cancer-related death 11 10 (91%) 1 (9%)   
a

One tumor specimen was of the baseloid type;therefore, its histological grade was not included in the analysis.

b

The nodal status of one patient was indeterminate(Nx) and therefore was not included in the analysis.

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