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Table 1

Tumor rechallenge of rats previously cured by laser immunotherapy treatment

GroupNo. of ratsNo. of tumor cellsTumor occurrence %Death rate % (in 30 days)Death rate % (in 40 days)Survival (days)
Young control ratsa 20 105 100 20 100 32.7± 3.5 
Age-matched control ratsb 18 106 100 83 100 28.2± 2.8 
Cured rats (1st challenge)c 15 106 >120 
Cured rats (2nd challenge)d 15 106 >120 
Cured rats (3rd challenge)e 15 106 >120 
GroupNo. of ratsNo. of tumor cellsTumor occurrence %Death rate % (in 30 days)Death rate % (in 40 days)Survival (days)
Young control ratsa 20 105 100 20 100 32.7± 3.5 
Age-matched control ratsb 18 106 100 83 100 28.2± 2.8 
Cured rats (1st challenge)c 15 106 >120 
Cured rats (2nd challenge)d 15 106 >120 
Cured rats (3rd challenge)e 15 106 >120 
a

Female Wistar Furth rats with tumor inoculation at the age of 8 weeks, with the normal tumor dose of 105 viable tumor cells.

b

Untreated rats of the same age as the cured rats at the time of inoculation, without previous exposure to tumor.

c

These tumor-bearing rats cured by laser-ICG-GC treatment were challenged with 106 viable tumor cells 120 days after the initial inoculation.

d

Successfully treated rats from different experimental groups were challenged the second time after the first challenge.

e

Successfully treated rats from different experimental groups were challenged the third time after the second challenge.

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