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Table 4

Relative risks for advanced breast cancer by number of CYP17 and HSD17B1 high-risk alleles by ethnicitya

Sample size and no. of high-risk allelesAfrican- AmericanLatinaWhiteJapanese
Controls (n = 1508) 459 485 277 287 
Stage 1 cases (n = 615) 135 138 170 172 
Stage 2 cases (n = 235) 68 51 64 52 
0b 1.00 (4)c 1.00 (2) 1.00 (2) 1.00 (7) 
1.49 (19) 3.14 (20) 1.95 (13) 0.53 (10) 
1.85 (27) 2.00 (16) 2.95 (29) 0.55 (15) 
1.98 (15) 1.91 (10) 3.60 (16) 1.02 (17) 
2.42 (3) 3.38 (3) 3.29 (4) 1.70 (3) 
Sample size and no. of high-risk allelesAfrican- AmericanLatinaWhiteJapanese
Controls (n = 1508) 459 485 277 287 
Stage 1 cases (n = 615) 135 138 170 172 
Stage 2 cases (n = 235) 68 51 64 52 
0b 1.00 (4)c 1.00 (2) 1.00 (2) 1.00 (7) 
1.49 (19) 3.14 (20) 1.95 (13) 0.53 (10) 
1.85 (27) 2.00 (16) 2.95 (29) 0.55 (15) 
1.98 (15) 1.91 (10) 3.60 (16) 1.02 (17) 
2.42 (3) 3.38 (3) 3.29 (4) 1.70 (3) 
a

Age and weight adjusted.

b

High risk alleles: CYP17, A2;HSD17B1, A.

c

Number of advanced stage cases by number of high-risk alleles.

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