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Table 3

The ErbB family mRNA expression, cut-off points, and comparison of survival using log-rank test for trend

Bladder tumors median (range) n = 73Cut-off point First SecondSurvival comparison (log rank test for trend)
AR (10−21 mol/μg RNA) 0.39 (0.0–23.50) 0.39 χ2 = 5.35 
  2.00 P < 0.02 
βCL (10−21 mol/μg RNA) 11.4 (0–1627) 11.4 NSa 
  30.0  
EPI (10−21 mol/μg RNA) 2.4 (0–144) 2.4 χ2 = 13.5 
  4.8 P < 0.0005 
HB-EGF (10−21 mol/μg RNA) 40.0 (0–2000) 40.0 χ2 = 6.6 
  70.0 P < 0.02 
TGF-α (10−21 mol/μg RNA) 1.4 (0–121) 1.4 χ2 = 8.6 
  7.0 P < 0.005 
HER1 (10−19 mol/μg RNA) 0.75 (0–85.1) 0.75 NS 
  3.00  
HER2 (10−18 mol/μg RNA) 390 (0–4570) 390 NS 
  1850  
Bladder tumors median (range) n = 73Cut-off point First SecondSurvival comparison (log rank test for trend)
AR (10−21 mol/μg RNA) 0.39 (0.0–23.50) 0.39 χ2 = 5.35 
  2.00 P < 0.02 
βCL (10−21 mol/μg RNA) 11.4 (0–1627) 11.4 NSa 
  30.0  
EPI (10−21 mol/μg RNA) 2.4 (0–144) 2.4 χ2 = 13.5 
  4.8 P < 0.0005 
HB-EGF (10−21 mol/μg RNA) 40.0 (0–2000) 40.0 χ2 = 6.6 
  70.0 P < 0.02 
TGF-α (10−21 mol/μg RNA) 1.4 (0–121) 1.4 χ2 = 8.6 
  7.0 P < 0.005 
HER1 (10−19 mol/μg RNA) 0.75 (0–85.1) 0.75 NS 
  3.00  
HER2 (10−18 mol/μg RNA) 390 (0–4570) 390 NS 
  1850  
a

NS, not significant.

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