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Table 4

Frequency distribution of NAT1 genotypes among 425 urinary bladder cancer patients and 343 controls

Expected frequencies are calculated from the allelic frequencies (Table 1) by the Hardy-Weinberg law.
Bladder cancerControls
NAT1 genotypeObservedObserved
 n n Expected % 
*3/*3 0.2 0.3 0.1 
*3/*4 18 4.2 14 4.1 4.4 
*3/*10 0.7 1.5 1.2 
*3/*11A 0.2 0.0 0.2 
*3/*11C 0.2 0.0 0.0 
*3/*14A 0.2 0.0 0.0 
*4/*4 241 56.7 175 51.0 52.5 
*4/*10 98 23.1 108 31.5 29.6 
*4/*11A 22 5.2 16 4.7 3.6 
*4/*11C 1.9 0.6 0.6 
*4/*14A 11 2.6 0.9 0.8 
*4/*17 0.2 0.3 0.2 
*4/*22 0.0 0.9 0.6 
*10/*10 1.9 12 3.5 4.2 
*10/*11A 0.7 0.3 1.0 
*10/*11C 0.2 0.3 0.2 
*10/*14A 0.9 0.3 0.2 
*10/*15 0.5 0.0 0.0 
*10/*17 0.2 0.0 0.1 
 ND     0.4 
 Total 425 100.0 343 100.0 100.0 
Expected frequencies are calculated from the allelic frequencies (Table 1) by the Hardy-Weinberg law.
Bladder cancerControls
NAT1 genotypeObservedObserved
 n n Expected % 
*3/*3 0.2 0.3 0.1 
*3/*4 18 4.2 14 4.1 4.4 
*3/*10 0.7 1.5 1.2 
*3/*11A 0.2 0.0 0.2 
*3/*11C 0.2 0.0 0.0 
*3/*14A 0.2 0.0 0.0 
*4/*4 241 56.7 175 51.0 52.5 
*4/*10 98 23.1 108 31.5 29.6 
*4/*11A 22 5.2 16 4.7 3.6 
*4/*11C 1.9 0.6 0.6 
*4/*14A 11 2.6 0.9 0.8 
*4/*17 0.2 0.3 0.2 
*4/*22 0.0 0.9 0.6 
*10/*10 1.9 12 3.5 4.2 
*10/*11A 0.7 0.3 1.0 
*10/*11C 0.2 0.3 0.2 
*10/*14A 0.9 0.3 0.2 
*10/*15 0.5 0.0 0.0 
*10/*17 0.2 0.0 0.1 
 ND     0.4 
 Total 425 100.0 343 100.0 100.0 

a ND, not detected.

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