Skip to Main Content
Table 1

β-catenin mutations in small (<1 cm) colorectal adenomas, large (≥1 cm) adenomas, and invasive carcinomas

The site of the tumor, age of the individual, and size (of the small adenomas) are also indicated.
Tumor IDSequence changeAmino acid changeaSitebAgeSize (mm)
Small adenomas (<1 cm)      
 SA 34 TCT to TTT Ser45 to Phe 70 
 SA 16 TCT to TTT Ser45 to Phe 69 
 SA 22 TCT to TTT Ser45 to Phe 62 
 SA 18 TCT to TTT Ser45 to Phe 57 
 SA 33 ACC to GCC Thr41 to Ala 66 
 SA 36 ACC to GCC Thr41 to Ala 64 
Large adenomas (≥1 cm)      
 LA 24 GGA to GAA Gly34 to Glu 72  
 LA 26 TCT to TTT Ser45 to Phe 79  
Invasive carcinomas      
 CA 53 ACC to GCC Thr41 to Ala 71  
The site of the tumor, age of the individual, and size (of the small adenomas) are also indicated.
Tumor IDSequence changeAmino acid changeaSitebAgeSize (mm)
Small adenomas (<1 cm)      
 SA 34 TCT to TTT Ser45 to Phe 70 
 SA 16 TCT to TTT Ser45 to Phe 69 
 SA 22 TCT to TTT Ser45 to Phe 62 
 SA 18 TCT to TTT Ser45 to Phe 57 
 SA 33 ACC to GCC Thr41 to Ala 66 
 SA 36 ACC to GCC Thr41 to Ala 64 
Large adenomas (≥1 cm)      
 LA 24 GGA to GAA Gly34 to Glu 72  
 LA 26 TCT to TTT Ser45 to Phe 79  
Invasive carcinomas      
 CA 53 ACC to GCC Thr41 to Ala 71  
a

Mutated exon 3 codon is indicated by superscript.

b

R, right-sided; L, left-sided.

Close Modal

or Create an Account

Close Modal
Close Modal