Table 3.

The association between the germline variant rs61757955 and genomic and histological variables

VariableMean or Percentage (Wild Type)Mean or Percentage (Mutant)P-value
CIC Mutated 15.9% 38.1% 0.017
1p/19q Co-deletion 25.2% 47.6% 0.038
Oligodendroglioma 33.7% 42.9% 0.475
Total Somatic Mutation Count 30.9 30.0 0.766
Percent Aneuploidy 15.1% 11.7% 0.524
Astrocytoma 38.1% 42.9% 0.651
IDH Mutated 78.1% 85.7% 0.583
1p/19q Co-deletion 25.2% 47.6% 0.038
MGMT Promoter Methylation 77.8% 81.0% 1.000
Chr 7 Gain/Chr 10 Loss 13.0% 9.5% 1.000
Expression of GRB2 (FPKM) 45.7 44.4 0.636
VariableMean or Percentage (Wild Type)Mean or Percentage (Mutant)P-value
CIC Mutated 15.9% 38.1% 0.017
1p/19q Co-deletion 25.2% 47.6% 0.038
Oligodendroglioma 33.7% 42.9% 0.475
Total Somatic Mutation Count 30.9 30.0 0.766
Percent Aneuploidy 15.1% 11.7% 0.524
Astrocytoma 38.1% 42.9% 0.651