Skip to Main Content
Table 2.

Comparison of nab-paclitaxel cycles 1 and 2 pharmacokinetics (n = 12)

Mean ratio (cycle 2/cycle 1)95% confidence intervalP
T1/2 (h) 0.93 0.76-1.10 0.28 
Cmax (ng/mL) 1.17 0.80-1.53 0.57 
AUCINF (h*ng/mL) 1.08 0.84-1.32 0.55 
Vz_obs (L/m2) 0.96 0.68-1.25 0.70 
Cl_obs (L/h/m2) 1.02 0.81-1.23 0.95 
Mean ratio (cycle 2/cycle 1)95% confidence intervalP
T1/2 (h) 0.93 0.76-1.10 0.28 
Cmax (ng/mL) 1.17 0.80-1.53 0.57 
AUCINF (h*ng/mL) 1.08 0.84-1.32 0.55 
Vz_obs (L/m2) 0.96 0.68-1.25 0.70 
Cl_obs (L/h/m2) 1.02 0.81-1.23 0.95 

NOTE: Cycle 1, initial cycle of nab-paclitaxel—either C1 or crossover C2. Cycle 2, third overall treatment cycle.

View Large
Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.
Accept