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Table 3.

Changes in tumor on CT and FDG-PET

After stopping gefitinib or erlotinibAfter restarting gefitinib or erlotinib3 wks after adding everolimus
Median change in tumor diameter +9% −1% −8% 
Mean change in tumor diameter +9% 1% −9% 
Range in change in tumor diameter −13% to +29% −14% to +23% −34% to +15% 
Median change in tumor volume +50% −1% −11% 
Mean change in tumor volume +61% −4% −10% 
Range in change in tumor volume −4% to +260% −27% to 15% −40% to +26% 
Median change in SUVmax +18% −4% −18% 
Mean change in SUVmax +23% −11% −11% 
Range in change in SUVmax −17% to +87% −45% to +62% −39% to +82% 
After stopping gefitinib or erlotinibAfter restarting gefitinib or erlotinib3 wks after adding everolimus
Median change in tumor diameter +9% −1% −8% 
Mean change in tumor diameter +9% 1% −9% 
Range in change in tumor diameter −13% to +29% −14% to +23% −34% to +15% 
Median change in tumor volume +50% −1% −11% 
Mean change in tumor volume +61% −4% −10% 
Range in change in tumor volume −4% to +260% −27% to 15% −40% to +26% 
Median change in SUVmax +18% −4% −18% 
Mean change in SUVmax +23% −11% −11% 
Range in change in SUVmax −17% to +87% −45% to +62% −39% to +82% 
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