Spearman rank correlation coefficients between baseline demographic and nicotine dependence and baseline plasma cotinine, 3-HC, and NMR (3-HC/COT)
| Variable . | COT . | 3-HC . | 3-HC/COT . |
|---|---|---|---|
| Age | 0.30 (0.047) | 0.35 (0.023) | 0.14 (0.359) |
| BMI | −0.11 (0.472) | −0.10 (0.526) | −0.11 (0.485) |
| FTND | 0.46 (0.002) | 0.23 (0.141) | −0.21 (0.169) |
| CPD | 0.37 (0.013) | 0.28 (0.064) | −0.04 (0.804) |
| TFC | −0.46 (0.002) | −0.21 (0.168) | 0.21 (0.183) |
| NDSSa | |||
| Overall score | 0.26 (0.094) | 0.11 (0.491) | −0.18 (0.253) |
| Continuity | 0.00 (0.976) | 0.08 (0.595) | 0.06 (0.721) |
| Drive | 0.15 (0.330) | −0.01 (0.956) | −0.20 (0.191) |
| Priority | −0.07 (0.670) | 0.09 (0.586) | 0.18 (0.261) |
| Stereotypy | 0.01 (0.949) | 0.03 (0.855) | 0.00 (0.999) |
| Tolerance | 0.32 (0.034) | 0.29 (0.055) | 0.01 (0.966) |
| Variable . | COT . | 3-HC . | 3-HC/COT . |
|---|---|---|---|
| Age | 0.30 (0.047) | 0.35 (0.023) | 0.14 (0.359) |
| BMI | −0.11 (0.472) | −0.10 (0.526) | −0.11 (0.485) |
| FTND | 0.46 (0.002) | 0.23 (0.141) | −0.21 (0.169) |
| CPD | 0.37 (0.013) | 0.28 (0.064) | −0.04 (0.804) |
| TFC | −0.46 (0.002) | −0.21 (0.168) | 0.21 (0.183) |
| NDSSa | |||
| Overall score | 0.26 (0.094) | 0.11 (0.491) | −0.18 (0.253) |
| Continuity | 0.00 (0.976) | 0.08 (0.595) | 0.06 (0.721) |
| Drive | 0.15 (0.330) | −0.01 (0.956) | −0.20 (0.191) |
| Priority | −0.07 (0.670) | 0.09 (0.586) | 0.18 (0.261) |
| Stereotypy | 0.01 (0.949) | 0.03 (0.855) | 0.00 (0.999) |
| Tolerance | 0.32 (0.034) | 0.29 (0.055) | 0.01 (0.966) |
aNDSS factors: Continuity, which taps the regularity of smoking; drive, which captures craving and withdrawal in abstinence; priority, which reflects the behavioral preference of smoking over other reinforcers; stereotypy, which gets at the invariance or the “sameness” of smoking; and tolerance, which measures the reduced sensitivity to smoking's effects (Shiffman and colleagues; ref. 29). Significant correlations are in bold font.