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Table 3.

Weight gain: multivariate regression among participants age 45+

Weight change fromCases (%)ControlsOR (95% CI)
Ages 25 to 40    
    Lost (≥ 0.1 kg/y) 4 (3%) 12 (8%) 0.38 (0.09-1.54) 
    No change (0 ± 0.1 kg/y) 13 (9%) 22 (14%) 1.00 
    Gain (0.1-0.5 kg/y) 49 (35%) 71 (46%) 1.07 (0.48-2.39) 
    Gain (0.5-1 kg/y) 33 (24%) 31 (20%) 1.62 (0.67-3.92) 
    Gain (>1 kg/y) 40 (29%) 18 (12%) 3.63 (1.46-9.04) 
    Mean change (kg/y) 0.78 0.44 P < 0.001 
Age 25 to diagnosis/interview    
    Lost (≥0.1 kg/y) 6 (4%) 7 (5%) 1.02 (0.27-3.88) 
    No change (0 ± 0.1 kg/y) 17 (12%) 23 (15%) 1.00 
    Gain (0.1-0.5 kg/y) 48 (35%) 73 (47%) 0.85 (0.41-1.80) 
    Gain 0.5-1 kg/y 53 (38%) 40 (26%) 1.78 (0.81-3.90) 
    Gain >1 kg/y 15 (11%) 12 (8%) 1.66 (0.58-4.79) 
    Mean change, kg/y 0.52 0.42 P = 0.05 
Age 40 to diagnosis/interview    
    Lost (≥0.1 kg/y) 31 (22%) 17 (11%) 2.43 (0.99-5.96) 
    No change (0 ± 0.1 kg/y) 21 (15%) 29 (18%) 1.00 
    Gain (0.1-0.5 kg/y) 43 (30%) 51 (32%) 1.26 (0.60-2.63) 
    Gain (0.5-1 kg/y) 28 (20%) 44 (28%) 0.86 (0.39-1.89) 
Gain (>1 kg/y) 20 (14%) 17 (11%) 1.57 (0.61-4.04) 
    Mean change (kg/y) 0.30 0.43 P = 0.2 
Weight change fromCases (%)ControlsOR (95% CI)
Ages 25 to 40    
    Lost (≥ 0.1 kg/y) 4 (3%) 12 (8%) 0.38 (0.09-1.54) 
    No change (0 ± 0.1 kg/y) 13 (9%) 22 (14%) 1.00 
    Gain (0.1-0.5 kg/y) 49 (35%) 71 (46%) 1.07 (0.48-2.39) 
    Gain (0.5-1 kg/y) 33 (24%) 31 (20%) 1.62 (0.67-3.92) 
    Gain (>1 kg/y) 40 (29%) 18 (12%) 3.63 (1.46-9.04) 
    Mean change (kg/y) 0.78 0.44 P < 0.001 
Age 25 to diagnosis/interview    
    Lost (≥0.1 kg/y) 6 (4%) 7 (5%) 1.02 (0.27-3.88) 
    No change (0 ± 0.1 kg/y) 17 (12%) 23 (15%) 1.00 
    Gain (0.1-0.5 kg/y) 48 (35%) 73 (47%) 0.85 (0.41-1.80) 
    Gain 0.5-1 kg/y 53 (38%) 40 (26%) 1.78 (0.81-3.90) 
    Gain >1 kg/y 15 (11%) 12 (8%) 1.66 (0.58-4.79) 
    Mean change, kg/y 0.52 0.42 P = 0.05 
Age 40 to diagnosis/interview    
    Lost (≥0.1 kg/y) 31 (22%) 17 (11%) 2.43 (0.99-5.96) 
    No change (0 ± 0.1 kg/y) 21 (15%) 29 (18%) 1.00 
    Gain (0.1-0.5 kg/y) 43 (30%) 51 (32%) 1.26 (0.60-2.63) 
    Gain (0.5-1 kg/y) 28 (20%) 44 (28%) 0.86 (0.39-1.89) 
Gain (>1 kg/y) 20 (14%) 17 (11%) 1.57 (0.61-4.04) 
    Mean change (kg/y) 0.30 0.43 P = 0.2 

NOTE: Adjusted for age, sex, ethnicity, agrochemical exposure, family history, and weight at ages 25 and 40.

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