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Table 2.

Relative hazards for incident and fatal prostate cancer by tertile of serum calcium in the NHANES Epidemiologic Follow-up Study

Tertile of serum calcium (median value)
Ptrend
Tertile 1 (9.3 mg/dL)Tertile 2 (9.7 mg/dL)Tertile 3 (10.1 mg/dL)
Prostate cancer incidence     
    No. incident cases 34 22 29  
    Person-years at risk 15,556 13,712 16,920  
    Age-adjusted relative hazards 1.00 (reference) 0.93 (0.54-1.60) 1.25 (0.76-2.07) 0.409 
        +BMI 1.00 (reference) 0.93 (0.54-1.60) 1.25 (0.76-2.07) 0.404 
        +Race 1.00 (reference) 0.93 (0.54-1.59) 1.29 (0.78-2.13) 0.361 
        +Family history 1.00 (reference) 0.97 (0.56-1.70) 1.31 (0.77-2.20) 0.341 
Prostate cancer mortality     
    No. fatal cases 11  
    Person-years at risk 15,556 13,712 16,920  
    Age-adjusted relative hazards 1.00 (reference) 1.64 (0.57-4.71) 2.59 (1.00-6.72) 0.049 
        +BMI 1.00 (reference) 1.66 (0.58-4.74) 2.62 (1.01-6.80) 0.046 
        +Race 1.00 (reference) 1.65 (0.58-4.72) 2.68 (1.02-6.99) 0.043 
        +Family history 1.00 (reference) 1.72 (0.55-5.37) 2.68 (0.94-7.64) 0.063 
Tertile of serum calcium (median value)
Ptrend
Tertile 1 (9.3 mg/dL)Tertile 2 (9.7 mg/dL)Tertile 3 (10.1 mg/dL)
Prostate cancer incidence     
    No. incident cases 34 22 29  
    Person-years at risk 15,556 13,712 16,920  
    Age-adjusted relative hazards 1.00 (reference) 0.93 (0.54-1.60) 1.25 (0.76-2.07) 0.409 
        +BMI 1.00 (reference) 0.93 (0.54-1.60) 1.25 (0.76-2.07) 0.404 
        +Race 1.00 (reference) 0.93 (0.54-1.59) 1.29 (0.78-2.13) 0.361 
        +Family history 1.00 (reference) 0.97 (0.56-1.70) 1.31 (0.77-2.20) 0.341 
Prostate cancer mortality     
    No. fatal cases 11  
    Person-years at risk 15,556 13,712 16,920  
    Age-adjusted relative hazards 1.00 (reference) 1.64 (0.57-4.71) 2.59 (1.00-6.72) 0.049 
        +BMI 1.00 (reference) 1.66 (0.58-4.74) 2.62 (1.01-6.80) 0.046 
        +Race 1.00 (reference) 1.65 (0.58-4.72) 2.68 (1.02-6.99) 0.043 
        +Family history 1.00 (reference) 1.72 (0.55-5.37) 2.68 (0.94-7.64) 0.063 

NOTE: Each model is adjusted for the listed variable and all prior variables.

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