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Table 2.

RR of bladder cancer according to BMI

VariableBMI (kg/m2)
Ptrend
18.5-24.925.0-29.930.0-34.9≥35.0
Person-years 1,174,879 1,474,882 541,963 212,917  
No. cases 479 845 301 94  
Age- and sex-adjusted RR (95% CI) 1.0 1.18 (1.05-1.32) 1.29 (1.11-1.49) 1.34 (1.08-1.68) 0.002 
Multivariate RR without physical activity (95% CI)* 1.0 1.16 (1.03-1.29) 1.23 (1.06-1.43) 1.30 (1.04-1.63) 0.016 
Multivariate RR with physical activity (95% CI) 1.0 1.15 (1.03-1.29) 1.22 (1.05-1.42) 1.28 (1.02-1.61) 0.028 
VariableBMI (kg/m2)
Ptrend
18.5-24.925.0-29.930.0-34.9≥35.0
Person-years 1,174,879 1,474,882 541,963 212,917  
No. cases 479 845 301 94  
Age- and sex-adjusted RR (95% CI) 1.0 1.18 (1.05-1.32) 1.29 (1.11-1.49) 1.34 (1.08-1.68) 0.002 
Multivariate RR without physical activity (95% CI)* 1.0 1.16 (1.03-1.29) 1.23 (1.06-1.43) 1.30 (1.04-1.63) 0.016 
Multivariate RR with physical activity (95% CI) 1.0 1.15 (1.03-1.29) 1.22 (1.05-1.42) 1.28 (1.02-1.61) 0.028 
*

The multivariate model used age as the underlying time metric and included the following covariates: gender (women, men), a combination of smoking status (never, former, current), time since quitting for former smokers (≥10, 5-9, 1-4, <1 y) and smoking intensity for former and current smokers (1-10, 11-20, 21-30, 31-40, 41-60, ≥61 cigarettes per day), race/ethnicity (White, Black, Hispanic, other race/ethnicity), education (less than high school, high school, vocational school or some college, college graduate, postgraduate), marital status (married or living as married, other), family history of cancer (yes, no), intakes of red meat (quintiles), fruit and vegetables combined (quintiles), nonalcoholic beverages (quintiles), and alcohol (0, <1, 1-3, >3 servings/d), menopausal hormone therapy (current, past, never), oral contraceptive use (ever, never), and parity (0, 1-2, ≥3).

Adjustment for physical activity included the following categories: 0, <1, 1-2, 3-4, ≥5 times a week.

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