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Table 5.

Hazard ratios (95% confidence intervals) for incident cancer and distribution of incident cancer cases (excluding nonmelanoma skin cancer) and corresponding person-time, by sex and sex-specific quintile of vegetable and fruit intakes combined; data from 25,623 adults of the Greek component of the EPIC study

Sex-specific quintiles of the corresponding variable
Q1Q2Q3Q4Q5Ordered quintiles
 Men (n = 10,582)      
Vegetables* and fruits       
    Quintile median 567 758 905 1069 1371  
    Person-time 14,819 15,179 15,184 15,238 15,641  
    Incident cancers 93 98 84 77 69  
    HR (95% CI) 1.10 (0.82-1.48) 0.93 (0.67-1.28) 0.89 (0.63-1.26) 0.87 (0.59-1.27) 0.95 (0.87-1.04) 
 Women (n = 15,041)      
Vegetables* and fruits       
    Quintile median 522 704 847 1011 1314  
    Person-time 21,858 22,210 22,372 22,480 23,060  
    Incident cancers 104 84 89 81 72  
    HR (95% CI) 0.79 (0.59-1.06) 0.84 (0.62-1.13) 0.74 (0.53-1.03) 0.61 (0.41-0.90) 0.90 (0.83-0.98) 
 Overall (n = 25,623)      
Vegetables* and fruits       
    Person-time 36,677 37,389 37,556 37,718 38,701  
    Incident cancers 197 182 173 158 141  
    HR (95% CI) 0.95 (0.77-1.16) 0.91 (0.73-1.13) 0.84 (0.66-1.07) 0.77 (0.59-1.01) 0.94 (0.88-0.99) 
Sex-specific quintiles of the corresponding variable
Q1Q2Q3Q4Q5Ordered quintiles
 Men (n = 10,582)      
Vegetables* and fruits       
    Quintile median 567 758 905 1069 1371  
    Person-time 14,819 15,179 15,184 15,238 15,641  
    Incident cancers 93 98 84 77 69  
    HR (95% CI) 1.10 (0.82-1.48) 0.93 (0.67-1.28) 0.89 (0.63-1.26) 0.87 (0.59-1.27) 0.95 (0.87-1.04) 
 Women (n = 15,041)      
Vegetables* and fruits       
    Quintile median 522 704 847 1011 1314  
    Person-time 21,858 22,210 22,372 22,480 23,060  
    Incident cancers 104 84 89 81 72  
    HR (95% CI) 0.79 (0.59-1.06) 0.84 (0.62-1.13) 0.74 (0.53-1.03) 0.61 (0.41-0.90) 0.90 (0.83-0.98) 
 Overall (n = 25,623)      
Vegetables* and fruits       
    Person-time 36,677 37,389 37,556 37,718 38,701  
    Incident cancers 197 182 173 158 141  
    HR (95% CI) 0.95 (0.77-1.16) 0.91 (0.73-1.13) 0.84 (0.66-1.07) 0.77 (0.59-1.01) 0.94 (0.88-0.99) 

NOTE: Data were adjusted for age (<35, 35-44, 45-54, 55-64, and >65 y; categorically), formal education (≤5, 6-11, 12, and ≥13 y; categorically), smoking status (never smoker, former smoker, and five categories of current smoker: 1-10, 11-20, 21-30, 31-40, and ≥41 cigarettes/d; ordered), body mass index (in ordered quintiles), height (in ordered quintiles), physical activity expressed in MET-hours per day (in ordered quintiles), alcohol intake (per 10 g/d; continuously), supplement intake (no, yes), and total daily energy intake (in ordered quintiles). For both genders overall stratified by sex.

*

Legumes are included.

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