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Table 2.

Family history of selected cancer sites and risk of lung cancer among nonsmokers

CasesPerson-yearsRR* (95% CI)
Any cancers 46 147.50 1.06 (0.76-1.48) 
    Parents 30 86.05 0.97 (0.65-1.45) 
    Siblings 25 85.26 1.70 (1.10-2.63) 
Tobacco-related cancers§ 18 67.57 1.13 (0.69-1.85) 
    Parents 12 40.65 1.02 (0.56-1.84) 
    Siblings 34.57 1.81 (0.88-3.72) 
Lung 24.58 0.89 (0.42-1.91) 
    Parents 10.36 0.69 (0.25-1.86) 
    Siblings 14.22 1.46 (0.46-4.59) 
Esophagus 29.48 1.80 (0.88-3.67) 
    Parents 24.53 1.96 (0.92-4.19) 
    Siblings 4.95 0.97 (0.14-6.97) 
Stomach 14 37.06 1.34 (0.77-2.33) 
    Parents 17.01 0.97 (0.45-2.08) 
    Siblings 20.05 2.16 (1.01-4.65) 
Colorectum 31.81 2.38 (1.21-4.70) 
    Parents 16.21 2.33 (1.02-5.28) 
    Siblings 15.60 2.63 (0.84-8.31) 
Liver 18.92 1.20 (0.56-2.57) 
    Parents 10.04 1.13 (0.42-3.05) 
    Siblings 8.87 1.32 (0.42-4.15) 
Pancreas 13.51 1.93 (0.62-6.07) 
    Parents 5.75 0.95 (0.13-6.83) 
    Siblings 7.76 4.19 (1.04-16.95) 
Breast 10.05 1.54 (0.63-3.76) 
    Parents 0.21 0.67 (0.09-4.77) 
    Siblings 9.85 2.45 (0.90-6.65) 
CasesPerson-yearsRR* (95% CI)
Any cancers 46 147.50 1.06 (0.76-1.48) 
    Parents 30 86.05 0.97 (0.65-1.45) 
    Siblings 25 85.26 1.70 (1.10-2.63) 
Tobacco-related cancers§ 18 67.57 1.13 (0.69-1.85) 
    Parents 12 40.65 1.02 (0.56-1.84) 
    Siblings 34.57 1.81 (0.88-3.72) 
Lung 24.58 0.89 (0.42-1.91) 
    Parents 10.36 0.69 (0.25-1.86) 
    Siblings 14.22 1.46 (0.46-4.59) 
Esophagus 29.48 1.80 (0.88-3.67) 
    Parents 24.53 1.96 (0.92-4.19) 
    Siblings 4.95 0.97 (0.14-6.97) 
Stomach 14 37.06 1.34 (0.77-2.33) 
    Parents 17.01 0.97 (0.45-2.08) 
    Siblings 20.05 2.16 (1.01-4.65) 
Colorectum 31.81 2.38 (1.21-4.70) 
    Parents 16.21 2.33 (1.02-5.28) 
    Siblings 15.60 2.63 (0.84-8.31) 
Liver 18.92 1.20 (0.56-2.57) 
    Parents 10.04 1.13 (0.42-3.05) 
    Siblings 8.87 1.32 (0.42-4.15) 
Pancreas 13.51 1.93 (0.62-6.07) 
    Parents 5.75 0.95 (0.13-6.83) 
    Siblings 7.76 4.19 (1.04-16.95) 
Breast 10.05 1.54 (0.63-3.76) 
    Parents 0.21 0.67 (0.09-4.77) 
    Siblings 9.85 2.45 (0.90-6.65) 
*

Adjusted for age, passive smoking, number of siblings, and number of children.

Adjusted for age and passive smoking.

Adjusted for age, passive smoking, and number of siblings.

§

Tobacco related cancers including cancer of the lung, oral cavity, pharynx, esophagus, pancreas, bladder, and kidney.

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