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Table 1.

Selected prostate cancer risk factors by use of cholesterol-lowering drugs, Cancer Prevention Study II Nutrition Cohort

Never use (n = 41,872), %Former use (n = 2,057), %Current use, <5 y (n = 6,653), %Current use, ≥5 y (n = 4,872), %
Age (y)     
    50-59 4.3 3.1 3.4 2.4 
    60-69 51.6 44.6 56.3 51.4 
    70-79 40.4 48.9 38.6 43.6 
    ≥80 3.7 3.5 1.7 2.5 
Race     
    White 97.8 96.8 98.1 97.9 
    Black 0.9 1.7 0.6 0.8 
    Other or unknown 1.2 1.5 1.4 1.3 
Education     
    <High school 7.2 8.6 6.8 6.1 
    High school graduate 18.2 18.7 17.9 17.7 
    Some college 25.1 27.5 26.2 25.2 
    College graduate 22.3 21.0 22.8 24.4 
    Graduate school 26.6 23.7 25.7 25.9 
    Unknown 0.6 0.4 0.6 0.7 
BMI     
    <25 34.5 33.9 30.6 30.4 
    25-<30 43.4 44.7 46.5 48.2 
    30-<35 11.6 11.3 12.3 12.0 
    ≥35 2.5 2.1 2.4 2.5 
    Unknown 7.9 8.0 8.2 6.9 
Family history of prostate cancer 17.0 14.5 16.0 15.2 
NSAID use (pills/mo)     
    None 34.3 25.3 17.8 17.8 
    1-14 23.8 22.9 22.5 22.6 
    15-29 8.5 8.6 6.7 7.8 
    30-59 14.6 18.3 24.6 24.8 
    ≥60 7.5 8.1 8.0 7.9 
    User, unknown quantity 11.2 16.8 20.4 19.1 
History of PSA testing     
    Never 17.4 13.0 11.9 10.1 
    Yes, test in last 2 y 63.8 63.9 71.1 73.7 
    Yes, test >2 y ago 10.5 12.0 8.9 8.9 
    Unknown 8.3 11.1 8.0 7.3 
Elevated cholesterol* 26.4 85.0 89.3 95.5 
Heart attack history 12.5 34.8 49.1 49.5 
Diabetes history 9.3 13.5 13.4 13.4 
Never use (n = 41,872), %Former use (n = 2,057), %Current use, <5 y (n = 6,653), %Current use, ≥5 y (n = 4,872), %
Age (y)     
    50-59 4.3 3.1 3.4 2.4 
    60-69 51.6 44.6 56.3 51.4 
    70-79 40.4 48.9 38.6 43.6 
    ≥80 3.7 3.5 1.7 2.5 
Race     
    White 97.8 96.8 98.1 97.9 
    Black 0.9 1.7 0.6 0.8 
    Other or unknown 1.2 1.5 1.4 1.3 
Education     
    <High school 7.2 8.6 6.8 6.1 
    High school graduate 18.2 18.7 17.9 17.7 
    Some college 25.1 27.5 26.2 25.2 
    College graduate 22.3 21.0 22.8 24.4 
    Graduate school 26.6 23.7 25.7 25.9 
    Unknown 0.6 0.4 0.6 0.7 
BMI     
    <25 34.5 33.9 30.6 30.4 
    25-<30 43.4 44.7 46.5 48.2 
    30-<35 11.6 11.3 12.3 12.0 
    ≥35 2.5 2.1 2.4 2.5 
    Unknown 7.9 8.0 8.2 6.9 
Family history of prostate cancer 17.0 14.5 16.0 15.2 
NSAID use (pills/mo)     
    None 34.3 25.3 17.8 17.8 
    1-14 23.8 22.9 22.5 22.6 
    15-29 8.5 8.6 6.7 7.8 
    30-59 14.6 18.3 24.6 24.8 
    ≥60 7.5 8.1 8.0 7.9 
    User, unknown quantity 11.2 16.8 20.4 19.1 
History of PSA testing     
    Never 17.4 13.0 11.9 10.1 
    Yes, test in last 2 y 63.8 63.9 71.1 73.7 
    Yes, test >2 y ago 10.5 12.0 8.9 8.9 
    Unknown 8.3 11.1 8.0 7.3 
Elevated cholesterol* 26.4 85.0 89.3 95.5 
Heart attack history 12.5 34.8 49.1 49.5 
Diabetes history 9.3 13.5 13.4 13.4 

NOTE: Percentages were adjusted to the age distribution of the entire study population.

*

Ever had elevated cholesterol, as self-reported by participants.

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