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Table 6.

DES exposure in relation to risk of breast cancer among women ages ≥40 years according to tumor characteristics

No. cases
Age-adjusted rate ratio (95% CI)
ExposedUnexposed
Estrogen receptor    
    Positive 43 13 1.92 (1.00-3.67) 
    Negative 1.76 (0.37-8.32) 
Progesterone receptor    
    Positive 35 10 2.06 (0.98-4.34) 
    Negative 13 2.12 (0.60-7.52) 
Histology    
    Ductal 49 14 1.94 (1.04-3.61) 
    Lobular — 
    Both — 
Tumor size    
    <2 cm 26 1.64 (0.75-3.59) 
    ≥2 cm 21 3.25 (1.03-10.2) 
Positive nodes    
    None 27 2.20 (0.95-5.11) 
    ≥1 22 2.10 (0.79-5.60) 
No. cases
Age-adjusted rate ratio (95% CI)
ExposedUnexposed
Estrogen receptor    
    Positive 43 13 1.92 (1.00-3.67) 
    Negative 1.76 (0.37-8.32) 
Progesterone receptor    
    Positive 35 10 2.06 (0.98-4.34) 
    Negative 13 2.12 (0.60-7.52) 
Histology    
    Ductal 49 14 1.94 (1.04-3.61) 
    Lobular — 
    Both — 
Tumor size    
    <2 cm 26 1.64 (0.75-3.59) 
    ≥2 cm 21 3.25 (1.03-10.2) 
Positive nodes    
    None 27 2.20 (0.95-5.11) 
    ≥1 22 2.10 (0.79-5.60) 
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