DES exposure in relation to risk of breast cancer among women ages ≥40 years according to tumor characteristics
| . | No. cases . | . | Age-adjusted rate ratio (95% CI) . | |||
|---|---|---|---|---|---|---|
| . | Exposed . | Unexposed . | . | |||
| Estrogen receptor | ||||||
| Positive | 43 | 13 | 1.92 (1.00-3.67) | |||
| Negative | 8 | 2 | 1.76 (0.37-8.32) | |||
| Progesterone receptor | ||||||
| Positive | 35 | 10 | 2.06 (0.98-4.34) | |||
| Negative | 13 | 3 | 2.12 (0.60-7.52) | |||
| Histology | ||||||
| Ductal | 49 | 14 | 1.94 (1.04-3.61) | |||
| Lobular | 2 | 1 | — | |||
| Both | 3 | 0 | — | |||
| Tumor size | ||||||
| <2 cm | 26 | 9 | 1.64 (0.75-3.59) | |||
| ≥2 cm | 21 | 4 | 3.25 (1.03-10.2) | |||
| Positive nodes | ||||||
| None | 27 | 8 | 2.20 (0.95-5.11) | |||
| ≥1 | 22 | 5 | 2.10 (0.79-5.60) | |||
| . | No. cases . | . | Age-adjusted rate ratio (95% CI) . | |||
|---|---|---|---|---|---|---|
| . | Exposed . | Unexposed . | . | |||
| Estrogen receptor | ||||||
| Positive | 43 | 13 | 1.92 (1.00-3.67) | |||
| Negative | 8 | 2 | 1.76 (0.37-8.32) | |||
| Progesterone receptor | ||||||
| Positive | 35 | 10 | 2.06 (0.98-4.34) | |||
| Negative | 13 | 3 | 2.12 (0.60-7.52) | |||
| Histology | ||||||
| Ductal | 49 | 14 | 1.94 (1.04-3.61) | |||
| Lobular | 2 | 1 | — | |||
| Both | 3 | 0 | — | |||
| Tumor size | ||||||
| <2 cm | 26 | 9 | 1.64 (0.75-3.59) | |||
| ≥2 cm | 21 | 4 | 3.25 (1.03-10.2) | |||
| Positive nodes | ||||||
| None | 27 | 8 | 2.20 (0.95-5.11) | |||
| ≥1 | 22 | 5 | 2.10 (0.79-5.60) | |||