American Association for Cancer Research

Table 3.

HLA markers independently associated with adult glioblastoma multiforme in multivariable analyses

HLA factors*	Model 1^†			Model 2^†
HLA factors*		OR (95% CI)	P	OR (95% CI)	P
B07-Cw07	2.79 (1.56-5.00)	<0.001	2.78 (1.55-4.98)	<0.001
HLA-B*13	7.07 (1.49-33.57)	0.014	7.53 (1.56-36.31)	0.012
HLA-Cw*01	0.35 (0.12-1.03)	0.057	0.33 (0.11-0.99)	0.047

HLA factors*	Model 1^†			Model 2^†
HLA factors*		OR (95% CI)	P	OR (95% CI)	P
B07-Cw07	2.79 (1.56-5.00)	<0.001	2.78 (1.55-4.98)	<0.001
HLA-B*13	7.07 (1.49-33.57)	0.014	7.53 (1.56-36.31)	0.012
HLA-Cw*01	0.35 (0.12-1.03)	0.057	0.33 (0.11-0.99)	0.047

Initially identified through univariate analyses (Table 2).

†

Model 1 includes all independent markers (i.e., those not explained by linkage disequilibrium); model 2 reflects further adjustment for age and gender.

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