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Table 3.

HLA markers independently associated with adult glioblastoma multiforme in multivariable analyses

HLA factors*Model 1
Model 2
OR (95% CI)POR (95% CI)P
B*07-Cw*07 2.79 (1.56-5.00) <0.001 2.78 (1.55-4.98) <0.001 
HLA-B*13 7.07 (1.49-33.57) 0.014 7.53 (1.56-36.31) 0.012 
HLA-Cw*01 0.35 (0.12-1.03) 0.057 0.33 (0.11-0.99) 0.047 
HLA factors*Model 1
Model 2
OR (95% CI)POR (95% CI)P
B*07-Cw*07 2.79 (1.56-5.00) <0.001 2.78 (1.55-4.98) <0.001 
HLA-B*13 7.07 (1.49-33.57) 0.014 7.53 (1.56-36.31) 0.012 
HLA-Cw*01 0.35 (0.12-1.03) 0.057 0.33 (0.11-0.99) 0.047 
*

Initially identified through univariate analyses (Table 2).

Model 1 includes all independent markers (i.e., those not explained by linkage disequilibrium); model 2 reflects further adjustment for age and gender.

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