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Table 2.

HLA markers provisionally associated with adult glioblastoma multiforme (GBA) through univariate analyses

HLA marker*Distribution, {n (%)} in:
OR (95% CI)Univariate P
155 Cases157 Controls
HLA-B*07 49 (31.6) 24 (15.3) 2.56 (1.48-4.44) <0.001 
HLA-B*13 10 (6.5) 2 (1.3) 5.34 (1.15-24.80) 0.020 
HLA-Cw*01 5 (3.2) 14 (8.9) 0.34 (0.12-0.97) 0.044 
B*07-Cw*07 45 (29.0) 21 (13.4) 2.65 (1.49-4.71) <0.001 
B*13-Cw*06 9 (5.8) 2 (1.3) 4.78 (1.02-22.48) 0.035 
HLA marker*Distribution, {n (%)} in:
OR (95% CI)Univariate P
155 Cases157 Controls
HLA-B*07 49 (31.6) 24 (15.3) 2.56 (1.48-4.44) <0.001 
HLA-B*13 10 (6.5) 2 (1.3) 5.34 (1.15-24.80) 0.020 
HLA-Cw*01 5 (3.2) 14 (8.9) 0.34 (0.12-0.97) 0.044 
B*07-Cw*07 45 (29.0) 21 (13.4) 2.65 (1.49-4.71) <0.001 
B*13-Cw*06 9 (5.8) 2 (1.3) 4.78 (1.02-22.48) 0.035 
*

Alleles and haplotypes tentatively associated with GBM, based on nominal P ≤ 0.05. OR, odds ratio; CI, confidence interval. Note that neither Cw*07 alone nor Cw*06 alone is associated with GBM (see text).

Based on maximum likelihood Chi-Square test unless specified otherwise.

By 2-sided, Fisher's exact test.

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