HLA markers provisionally associated with adult glioblastoma multiforme (GBA) through univariate analyses
HLA marker* . | Distribution, {n (%)} in: . | . | OR (95% CI) . | Univariate P† . | |
---|---|---|---|---|---|
. | 155 Cases . | 157 Controls . | . | . | |
HLA-B*07 | 49 (31.6) | 24 (15.3) | 2.56 (1.48-4.44) | <0.001 | |
HLA-B*13 | 10 (6.5) | 2 (1.3) | 5.34 (1.15-24.80) | 0.020‡ | |
HLA-Cw*01 | 5 (3.2) | 14 (8.9) | 0.34 (0.12-0.97) | 0.044 | |
B*07-Cw*07 | 45 (29.0) | 21 (13.4) | 2.65 (1.49-4.71) | <0.001 | |
B*13-Cw*06 | 9 (5.8) | 2 (1.3) | 4.78 (1.02-22.48) | 0.035‡ |
HLA marker* . | Distribution, {n (%)} in: . | . | OR (95% CI) . | Univariate P† . | |
---|---|---|---|---|---|
. | 155 Cases . | 157 Controls . | . | . | |
HLA-B*07 | 49 (31.6) | 24 (15.3) | 2.56 (1.48-4.44) | <0.001 | |
HLA-B*13 | 10 (6.5) | 2 (1.3) | 5.34 (1.15-24.80) | 0.020‡ | |
HLA-Cw*01 | 5 (3.2) | 14 (8.9) | 0.34 (0.12-0.97) | 0.044 | |
B*07-Cw*07 | 45 (29.0) | 21 (13.4) | 2.65 (1.49-4.71) | <0.001 | |
B*13-Cw*06 | 9 (5.8) | 2 (1.3) | 4.78 (1.02-22.48) | 0.035‡ |
Alleles and haplotypes tentatively associated with GBM, based on nominal P ≤ 0.05. OR, odds ratio; CI, confidence interval. Note that neither Cw*07 alone nor Cw*06 alone is associated with GBM (see text).
Based on maximum likelihood Chi-Square test unless specified otherwise.
By 2-sided, Fisher's exact test.