Skip to Main Content
Table 1.

Analyses of human leukocyte antigen (HLA) and TNFb microsatellite variants previously associated with malignant glioma and related diseases in various cohorts

Genetic variantsReported associationDistribution, {n (%)} in:
ORP*
155 Cases157 Controls
A24 Positive 24 (15.5) 25 (15.9) 0.97 0.92 
A*25 Positive 6 (3.9) 8 (5.1) 0.75 0.60 
B*27 Positive 11 (7.1) 11 (7.0) 1.01 0.97 
DRB1*15 Positive 39 (25.2) 39 (24.8) 1.02 0.95 
DRB1*07 Negative 34 (21.9) 38 (24.2) 0.88 0.63 
Cw*06-DRB1*07 Negative 13 (8.4) 11 (7.0) 1.22 0.65 
TNFb allele 4 (b4) hmz§ Positive 33 (21.3) 23 (14.6) 1.58 0.13 
Genetic variantsReported associationDistribution, {n (%)} in:
ORP*
155 Cases157 Controls
A24 Positive 24 (15.5) 25 (15.9) 0.97 0.92 
A*25 Positive 6 (3.9) 8 (5.1) 0.75 0.60 
B*27 Positive 11 (7.1) 11 (7.0) 1.01 0.97 
DRB1*15 Positive 39 (25.2) 39 (24.8) 1.02 0.95 
DRB1*07 Negative 34 (21.9) 38 (24.2) 0.88 0.63 
Cw*06-DRB1*07 Negative 13 (8.4) 11 (7.0) 1.22 0.65 
TNFb allele 4 (b4) hmz§ Positive 33 (21.3) 23 (14.6) 1.58 0.13 
*

Based on maximum likelihood Chi-square tests.

From a study of 42 Japanese patients (39).

From a study of 65 German patients (41).

§

Hmz, homozygosity, from a study of 48 Italian patients (40).

Close Modal

or Create an Account

Close Modal
Close Modal