Characteristics of studies on mammographic features in relation to breast cancer risk conducted in symptomatic populations
| First author, y (ref.) . | Study design. Study population characteristics. Matching variables if applicable (Match). Variables adjusted for in analysis (Adj) . | No. cases: noncases . | Age (y) . | Mammographic feature . | ||||
|---|---|---|---|---|---|---|---|---|
| Studies using prospective (prediagnostic) mammograms | ||||||||
| Wolfe, 1976 (62) | Cohort: mammography attendees at Hutzel hospital, United States; cases diagnosed 0.5-3.5 y after negative mammogram. | 30-60+ | Wolfe | |||||
| Study 1 | 1967-1974 | 20:1,910 | ||||||
| Study 2 | 1972-1975. Adj: none. | 56:5,228 | ||||||
| Egan, 1979 (60) | Cohort: referrals to Emory University Clinic, United States, 1963-1977; cases diagnosed at least 0.5 y after negative mammogram. Adj: A. | 131:6,334 | 35-70+ | Wolfe | ||||
| Studies using concurrent (diagnostic) mammograms | ||||||||
| Peyster, 1977 (63) | CC. Cases and controls: referrals to Massachusetts General Hospital, United States, 1972-1976. Adj: A. | 402:1,036 | 30-60+ | Wolfe | ||||
| Brebner, 1978 (65) | XS. Referrals for mammography at Johannesburg General Hospital, South Africa. Adj: A. | 300:2,702 | <20-60+ | Wolfe | ||||
| Egan, 1979 (60) | XS. As for Egan 1979, but cases diagnosis and timing of breast density measurement are concurrent. Adj: A. | 658:13,465 | 30-70+ | Wolfe | ||||
| Boyd, 1982 (64) | CC. Cases: Women's College Hospital, Canada, 1973-1979; controls: diagnostic referral service. Match: A, YR. | 183:183 | 40-65 | Wolfe | ||||
| Tabar, 1982 (49) | CC. Cases: Kopparberg County screening program, Sweden; controls: referred for mammography. Adj: A. | 183:1,674 | 40-75+ | Wolfe | ||||
| Kojima, 1984 (61) | XS. Women who underwent xeromammography at Kyoto Prefectual University of Medicine, Japan, 1978-1982. Majority had clinical breast disease. Adj: A. | 91:746 | 30-60+ | Wolfe | ||||
| Wolfe, 1987 (31) | MCC. Cases: Hutzel hospital, United States, 1979-1982; controls: screened at the same hospital, generally symptomatic. Match: YR, A, R, AFB, FH. Adj: no other. | 160:160 | 30-85 | Wolfe, PD | ||||
| First author, y (ref.) . | Study design. Study population characteristics. Matching variables if applicable (Match). Variables adjusted for in analysis (Adj) . | No. cases: noncases . | Age (y) . | Mammographic feature . | ||||
|---|---|---|---|---|---|---|---|---|
| Studies using prospective (prediagnostic) mammograms | ||||||||
| Wolfe, 1976 (62) | Cohort: mammography attendees at Hutzel hospital, United States; cases diagnosed 0.5-3.5 y after negative mammogram. | 30-60+ | Wolfe | |||||
| Study 1 | 1967-1974 | 20:1,910 | ||||||
| Study 2 | 1972-1975. Adj: none. | 56:5,228 | ||||||
| Egan, 1979 (60) | Cohort: referrals to Emory University Clinic, United States, 1963-1977; cases diagnosed at least 0.5 y after negative mammogram. Adj: A. | 131:6,334 | 35-70+ | Wolfe | ||||
| Studies using concurrent (diagnostic) mammograms | ||||||||
| Peyster, 1977 (63) | CC. Cases and controls: referrals to Massachusetts General Hospital, United States, 1972-1976. Adj: A. | 402:1,036 | 30-60+ | Wolfe | ||||
| Brebner, 1978 (65) | XS. Referrals for mammography at Johannesburg General Hospital, South Africa. Adj: A. | 300:2,702 | <20-60+ | Wolfe | ||||
| Egan, 1979 (60) | XS. As for Egan 1979, but cases diagnosis and timing of breast density measurement are concurrent. Adj: A. | 658:13,465 | 30-70+ | Wolfe | ||||
| Boyd, 1982 (64) | CC. Cases: Women's College Hospital, Canada, 1973-1979; controls: diagnostic referral service. Match: A, YR. | 183:183 | 40-65 | Wolfe | ||||
| Tabar, 1982 (49) | CC. Cases: Kopparberg County screening program, Sweden; controls: referred for mammography. Adj: A. | 183:1,674 | 40-75+ | Wolfe | ||||
| Kojima, 1984 (61) | XS. Women who underwent xeromammography at Kyoto Prefectual University of Medicine, Japan, 1978-1982. Majority had clinical breast disease. Adj: A. | 91:746 | 30-60+ | Wolfe | ||||
| Wolfe, 1987 (31) | MCC. Cases: Hutzel hospital, United States, 1979-1982; controls: screened at the same hospital, generally symptomatic. Match: YR, A, R, AFB, FH. Adj: no other. | 160:160 | 30-85 | Wolfe, PD | ||||
Abbreviations: CC, case-control; A, age; AFB, age at first birth; FH, family history of breast cancer; R, race/ethnicity; WT, weight; YR, year; MCC, matched case-control; XS, cross-sectional study.