Table 2.

Patient characteristics and ductal lavage cytology results

Patient characteristics*Insufficient cellular material for diagnosis (n = 8)Benign cells (n = 35)Two-sided P value,Atypical cells (n = 17)Two-sided P value,§
Median age (years) 44.5 42 0.072 38 0.63 
Prior breast cancer 5 (62.5%) 5 (14.3%) 0.01 4 (23.5%) 0.45 
Prior ovarian cancer 0 (0%) 3 (8.6%) 1.0 3 (17.7%) 0.38 
Prior breast or ovarian cancer 5 (62.5%) 8 (22.9%) 0.042 7 (41.2%) 0.20 
Prior chemotherapy 5 (62.5%) 7 (20.0%) 0.028 7 (41.2%) 0.18 
Prior breast radiation 3 (37.5%) 3 (8.6%) 0.067 3 (17.7%) 0.38 
Ever fluid-yielding on suction aspiration 1 (12.5%) 19 (54.3%) 0.05 9 (52.9%) 1.0 
Patient characteristics*Insufficient cellular material for diagnosis (n = 8)Benign cells (n = 35)Two-sided P value,Atypical cells (n = 17)Two-sided P value,§
Median age (years) 44.5 42 0.072 38 0.63 
Prior breast cancer 5 (62.5%) 5 (14.3%) 0.01 4 (23.5%) 0.45 
Prior ovarian cancer 0 (0%) 3 (8.6%) 1.0 3 (17.7%) 0.38 
Prior breast or ovarian cancer 5 (62.5%) 8 (22.9%) 0.042 7 (41.2%) 0.20 
Prior chemotherapy 5 (62.5%) 7 (20.0%) 0.028 7 (41.2%) 0.18 
Prior breast radiation 3 (37.5%) 3 (8.6%) 0.067 3 (17.7%) 0.38 
Ever fluid-yielding on suction aspiration 1 (12.5%) 19 (54.3%) 0.05 9 (52.9%) 1.0 
*

There were no significant differences between groups in BRCA mutation status, prior or current selective estrogen response modulator, oral contraceptive, and hormone replacement therapy use, parity, prior breast-feeding, menopausal status, bilateral salpingo-oophorectomy before ductal lavage, and prior breast biopsy.

Two-sided P values from Fisher's exact test for categorical variables and Mann-Whitney U test for continuous variables.

For comparison of patients with insufficient cellular material for diagnosis versus patients with benign cells.

§

For comparison of patients with benign cells versus patients with atypical cells.

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