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Table 2.

The type-specific prevalence of HPV in HNSCCs by cancer site

Oral cavity* (n = 2,642)
Oropharynx* (n = 969)
Larynx*, (n = 1,435)
Positive/testedPrevalence (%)Positive/testedPrevalence (%)Positive/testedPrevalence (%)
6 59/1,884 3.1 18/706 2.5 52/1,028 5.1 
11 31/1,904 1.6 5/705 0.7 5/1,015 0.5 
16 423/2,642 16.0 299/969 30.9 238/1,435 16.6 
18 212/2,642 8.0 9/909 1.0 54/1,387 3.9 
16 and 18 44/2,642 1.7 1/909 0.1 6/1,387 0.4 
31 3/1,422 0.2 0/656 0.0 2/797 0.3 
32 1/496 0.2 0/287 0.0 0/178 0.0 
33 14/1,678 0.8 9/802 1.1 9/1,051 0.9 
35 1/1,350 0.1 2/568 0.4 0/496 0.0 
39 0/1,335 0.0 0/496 0.0 0/300 0.0 
44 1/1,290 0.1 0/466 0.0 0/291 0.0 
45 0/1,362 0.0 1/559 0.2 1/439 0.2 
51 0/1,350 0.0 0/568 0.0 1/336 0.3 
52 0/1,335 0.0 0/496 0.0 1/443 0.2 
53 1/539 0.2 0/329 0.0 0/327 0.0 
56 2/1,350 0.1 0/568 0.0 0/296 0.0 
57 1/393 0.3 0/220 0.0 0/263 0.0 
58 1/1,335 0.1 0/563 0.0 0/443 0.0 
59 0/1,335 0.0 1/496 0.2 0/300 0.0 
68 1/1,335 0.1 0/496 0.0 0/260 0.0 
73 0/524 0.0 0/225 0.0 0/206 0.0 
81 1/405 0.2 0/220 0.0 0/178 0.0 
82 0/496 0.0 0/220 0.0 0/178 0.0 
Oral cavity* (n = 2,642)
Oropharynx* (n = 969)
Larynx*, (n = 1,435)
Positive/testedPrevalence (%)Positive/testedPrevalence (%)Positive/testedPrevalence (%)
6 59/1,884 3.1 18/706 2.5 52/1,028 5.1 
11 31/1,904 1.6 5/705 0.7 5/1,015 0.5 
16 423/2,642 16.0 299/969 30.9 238/1,435 16.6 
18 212/2,642 8.0 9/909 1.0 54/1,387 3.9 
16 and 18 44/2,642 1.7 1/909 0.1 6/1,387 0.4 
31 3/1,422 0.2 0/656 0.0 2/797 0.3 
32 1/496 0.2 0/287 0.0 0/178 0.0 
33 14/1,678 0.8 9/802 1.1 9/1,051 0.9 
35 1/1,350 0.1 2/568 0.4 0/496 0.0 
39 0/1,335 0.0 0/496 0.0 0/300 0.0 
44 1/1,290 0.1 0/466 0.0 0/291 0.0 
45 0/1,362 0.0 1/559 0.2 1/439 0.2 
51 0/1,350 0.0 0/568 0.0 1/336 0.3 
52 0/1,335 0.0 0/496 0.0 1/443 0.2 
53 1/539 0.2 0/329 0.0 0/327 0.0 
56 2/1,350 0.1 0/568 0.0 0/296 0.0 
57 1/393 0.3 0/220 0.0 0/263 0.0 
58 1/1,335 0.1 0/563 0.0 0/443 0.0 
59 0/1,335 0.0 1/496 0.2 0/300 0.0 
68 1/1,335 0.1 0/496 0.0 0/260 0.0 
73 0/524 0.0 0/225 0.0 0/206 0.0 
81 1/405 0.2 0/220 0.0 0/178 0.0 
82 0/496 0.0 0/220 0.0 0/178 0.0 

NOTE: HPV types considered “high-risk” are in bold.

Abbreviations: HPV, human papillomaviruses; HNSCCs, head and neck squamous cell carcinomas.

*

Columns do not sum to total number of HPV-positive cases because multiple infections were broken down into constituent types. Columns sum to total number of infections in study population.

Larynx includes cases of the hypopharynx.

HPV types considered to confer low or intermediate risk based on cervical cancer studies (4).

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