Variables independently predicting association of a nevus with cutaneous malignant melanoma (N = 932) in a multivariable analysis
| Characteristic . | Category . | OR* (95% CI) . | P . | Ptrend . |
|---|---|---|---|---|
| Study center | Ontario | 1.0 | 0.80 | — |
| British Columbia | 1.0 (0.6-1.6) | |||
| New South Wales | 1.1 (0.8-1.5) | |||
| Sex | Female | 1.0 | 0.80 | — |
| Male | 1.0 (0.7-1.5) | |||
| Age | <40 | 1.0 | 0.79 | 0.41 |
| 40-54 | 1.1 (0.7-1.7) | |||
| 55-69 | 1.1 (0.7-1.8) | |||
| 70+ | 0.9 (0.5-1.6) | |||
| Breslow thickness | ≤0.75 | 1.0 | 0.25 | 0.17 |
| 0.76-1.50 | 0.7 (0.5-1.0) | |||
| 1.51-4.00 | 0.9 (0.6-1.5) | |||
| >4.00 | 0.5 (0.2-1.4) | |||
| Skin tendency to tan | Dark tan | 1.0 | 0.15 | 0.84 |
| Moderate tan | 1.0 (0.7-1.5) | |||
| Mild tan | 0.7 (0.5-1.2) | |||
| No suntan/freckling | 1.3 (0.7-2.5) | |||
| Histologic subtype | SSM | 1.0 | 0.008 | — |
| NM | 0.6 (0.3-1.0) | |||
| LMM | 0.4 (0.2-0.9) | |||
| Other/NOS | 0.5 (0.2-1.3) | |||
| Nevus density (body diagrams) | No nevi | 1.0 | 0.05 | 0.06 |
| Low | 1.5 (1.1-2.3) | |||
| Moderate | 1.2 (0.7-2.1) | |||
| High | 2.3 (1.1-4.8) | |||
| Anatomic location of melanoma | Trunk | 1.0 | 0.0009 | — |
| Head/neck | 0.6 (0.3-1.1) | |||
| Upper limb | 0.5 (0.3-0.8) | |||
| Lower limb | 0.4 (0.3-0.7) | |||
| Other/NOS | 0.5 (0.2-1.3) | |||
| Solar elastosis in adjacent tissue | None | 1.0 | 0.18 | 0.11 |
| Mild/moderate | 0.9 (0.6-1.2) | |||
| Marked | 0.5 (0.2-1.0) |
| Characteristic . | Category . | OR* (95% CI) . | P . | Ptrend . |
|---|---|---|---|---|
| Study center | Ontario | 1.0 | 0.80 | — |
| British Columbia | 1.0 (0.6-1.6) | |||
| New South Wales | 1.1 (0.8-1.5) | |||
| Sex | Female | 1.0 | 0.80 | — |
| Male | 1.0 (0.7-1.5) | |||
| Age | <40 | 1.0 | 0.79 | 0.41 |
| 40-54 | 1.1 (0.7-1.7) | |||
| 55-69 | 1.1 (0.7-1.8) | |||
| 70+ | 0.9 (0.5-1.6) | |||
| Breslow thickness | ≤0.75 | 1.0 | 0.25 | 0.17 |
| 0.76-1.50 | 0.7 (0.5-1.0) | |||
| 1.51-4.00 | 0.9 (0.6-1.5) | |||
| >4.00 | 0.5 (0.2-1.4) | |||
| Skin tendency to tan | Dark tan | 1.0 | 0.15 | 0.84 |
| Moderate tan | 1.0 (0.7-1.5) | |||
| Mild tan | 0.7 (0.5-1.2) | |||
| No suntan/freckling | 1.3 (0.7-2.5) | |||
| Histologic subtype | SSM | 1.0 | 0.008 | — |
| NM | 0.6 (0.3-1.0) | |||
| LMM | 0.4 (0.2-0.9) | |||
| Other/NOS | 0.5 (0.2-1.3) | |||
| Nevus density (body diagrams) | No nevi | 1.0 | 0.05 | 0.06 |
| Low | 1.5 (1.1-2.3) | |||
| Moderate | 1.2 (0.7-2.1) | |||
| High | 2.3 (1.1-4.8) | |||
| Anatomic location of melanoma | Trunk | 1.0 | 0.0009 | — |
| Head/neck | 0.6 (0.3-1.1) | |||
| Upper limb | 0.5 (0.3-0.8) | |||
| Lower limb | 0.4 (0.3-0.7) | |||
| Other/NOS | 0.5 (0.2-1.3) | |||
| Solar elastosis in adjacent tissue | None | 1.0 | 0.18 | 0.11 |
| Mild/moderate | 0.9 (0.6-1.2) | |||
| Marked | 0.5 (0.2-1.0) |
Adjusted for all variables shown in table.