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Table 1.

Per3 genotypes and breast cancer risk stratified by menopausal status

Genotypes*Cases, N (%)Controls, N (%)OR (95% CI)
Overall    
    −/− 180 (46.2) 206 (47.7) 1.0 
    +/− 173 (44.5) 198 (45.8) 1.1 (0.8-1.4) 
    +/+ 36 (9.3) 28 ( 6.5) 1.5 (0.9-2.5) 
    +/− and +/+ 209 (53.8) 226 (52.3) 1.1 (0.8-1.5) 
Premenopausal Women    
    −/− 33 (37.5) 76 (51.0) 1.0 
    +/− 47 (53.4) 64 (43.0) 1.7 (1.0-3.0) 
    +/+ 8 (9.1) 9 ( 6.0) 1.8 (0.6-5.3) 
    +/− and +/+ 55 (62.5) 73 (49.0) 1.7 (1.0-3.0) 
Postmenopausal Women    
    −/− 147 (48.8) 130 (45.9) 1.0 
    +/− 126 (41.9) 134 (47.4) 0.9 (0.6-1.2) 
    +/+ 28 (9.3) 19 (6.7) 1.4 (0.7-2.6) 
    +/− and +/+ 154 (51.2) 153 (54.1) 0.9 (0.7-1.3) 
Genotypes*Cases, N (%)Controls, N (%)OR (95% CI)
Overall    
    −/− 180 (46.2) 206 (47.7) 1.0 
    +/− 173 (44.5) 198 (45.8) 1.1 (0.8-1.4) 
    +/+ 36 (9.3) 28 ( 6.5) 1.5 (0.9-2.5) 
    +/− and +/+ 209 (53.8) 226 (52.3) 1.1 (0.8-1.5) 
Premenopausal Women    
    −/− 33 (37.5) 76 (51.0) 1.0 
    +/− 47 (53.4) 64 (43.0) 1.7 (1.0-3.0) 
    +/+ 8 (9.1) 9 ( 6.0) 1.8 (0.6-5.3) 
    +/− and +/+ 55 (62.5) 73 (49.0) 1.7 (1.0-3.0) 
Postmenopausal Women    
    −/− 147 (48.8) 130 (45.9) 1.0 
    +/− 126 (41.9) 134 (47.4) 0.9 (0.6-1.2) 
    +/+ 28 (9.3) 19 (6.7) 1.4 (0.7-2.6) 
    +/− and +/+ 154 (51.2) 153 (54.1) 0.9 (0.7-1.3) 
*

−/− Homozygous 4-repeat allele; +/− heterozygous alleles; +/+ homozygous 5-repeat allele.

Adjusted for age, family history of breast cancer, family income, body mass, age at menarche, age at first birth, and county.

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