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Table 3.

Adjusted ORs and 95% CIs for associations between IGF1 (CA)19 repeat and IGFBP3 −202 A/C genotypes in DVAMC prostate cancer cases and controls

Overall*
Blacks*
Whites*
No. cases/no. controlsOR (95% CI)No. cases/no. controlsOR (95% CI)No. cases/no. controlsOR (95% CI)
IGF1 (CA)19 genotypes       
(CA)19/(CA)19 20/28 0.3 (0.1-0.7) 3/9 0.2 (0.0-0.8) 17/19 0.4 (0.1-1.6) 
(CA)19/x 39/33 0.6 (0.3-1.4) 19/17 0.7 (0.3-1.7) 20/16 0.7 (0.2-2.4) 
x/x 35/20 1.0 (reference) 25/15 1.0 (reference) 10/5 1.0 (reference) 
IGFBP3 -202 A/C genotypes       
CC 26/26 1.3 (0.6-3.1) 11/11 1.5 (0.4-5.1) 15/15 1.0 (0.3-3.5) 
AC 53/39 1.9 (0.9-4.1) 29/20 2.9 (1.0-8.6) 24/19 1.0 (0.3-3.3) 
AA 18/23 1.0 (reference) 9/15 1.0 (reference) 9/8 1.0 (reference) 
IGFBP3 -202 A/C genotypes       
CC/AC 79/65 1.7 (0.8-3.4) 40/31 2.3 (0.8-6.2) 39/34 1.0 (0.3-3.1) 
AA 18/23 1.0 (reference) 9/15 1.0 (reference) 9/8 1.0 (reference) 
Overall*
Blacks*
Whites*
No. cases/no. controlsOR (95% CI)No. cases/no. controlsOR (95% CI)No. cases/no. controlsOR (95% CI)
IGF1 (CA)19 genotypes       
(CA)19/(CA)19 20/28 0.3 (0.1-0.7) 3/9 0.2 (0.0-0.8) 17/19 0.4 (0.1-1.6) 
(CA)19/x 39/33 0.6 (0.3-1.4) 19/17 0.7 (0.3-1.7) 20/16 0.7 (0.2-2.4) 
x/x 35/20 1.0 (reference) 25/15 1.0 (reference) 10/5 1.0 (reference) 
IGFBP3 -202 A/C genotypes       
CC 26/26 1.3 (0.6-3.1) 11/11 1.5 (0.4-5.1) 15/15 1.0 (0.3-3.5) 
AC 53/39 1.9 (0.9-4.1) 29/20 2.9 (1.0-8.6) 24/19 1.0 (0.3-3.3) 
AA 18/23 1.0 (reference) 9/15 1.0 (reference) 9/8 1.0 (reference) 
IGFBP3 -202 A/C genotypes       
CC/AC 79/65 1.7 (0.8-3.4) 40/31 2.3 (0.8-6.2) 39/34 1.0 (0.3-3.1) 
AA 18/23 1.0 (reference) 9/15 1.0 (reference) 9/8 1.0 (reference) 
*

Frequencies exclude subjects with missing values for any of the adjustment variables.

OR adjusted for age, body mass index, height, and diabetes (also race in the overall analyses).

x, non-(CA)19 allele.

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