Frequencies of IGF1 CA repeat alleles and genotypes and IGFBP3 −202 A/C genotypes in DVAMC prostate cancer cases and controls
. | Overall . | . | Blacks . | . | Whites . | . | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
. | Cases, n = 100 (%) . | Controls, n = 93 (%) . | Cases, n = 50 (%) . | Controls, n = 49 (%) . | Cases, n = 50 (%) . | Controls, n = 44 (%) . | ||||||
IGF1 CA repeat allele frequencies* | ||||||||||||
(CA)11 | 0 (0.0) | 1 (0.6) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (1.2) | ||||||
(CA)16 | 2 (1.0) | 9 (5.4) | 2 (2.1) | 9 (10.5) | 0 (0.0) | 0 (0.0) | ||||||
(CA)17 | 8 (4.1) | 5 (3.0) | 5 (5.2) | 3 (3.5) | 3 (3.1) | 2 (2.4) | ||||||
(CA)18 | 39 (20.1) | 23 (13.7) | 34 (35.4) | 17 (19.8) | 5 (5.1) | 6 (7.3) | ||||||
(CA)19 | 84 (43.3) | 91 (54.2) | 27 (28.1) | 36 (41.9) | 57 (58.2) | 55 (67.1) | ||||||
(CA)20 | 41 (21.1) | 24 (14.3) | 14 (14.6) | 10 (11.6) | 27 (27.6) | 14 (17.1) | ||||||
(CA)21 | 15 (7.7) | 12 (7.1) | 12 (12.5) | 9 (10.5) | 3 (3.1) | 3 (3.7) | ||||||
(CA)22 | 3 (1.6) | 2 (1.2) | 0 (0.0) | 1 (1.2) | 3 (3.1) | 1 (1.2) | ||||||
(CA)24 | 2 (1.0) | 1 (0.6) | 2 (2.1) | 1 (1.2) | 0 (0.0) | 0 (0.0) | ||||||
Missing | 6 | 18 | 4 | 12 | 2 | 6 | ||||||
IGF1 CA repeat genotype | ||||||||||||
(CA)19/(CA)19 | 22 (22.7) | 28 (33.3) | 4 (8.3) | 9 (20.9) | 18 (36.7) | 19 (46.3) | ||||||
(CA)19/x | 40 (41.2) | 35 (41.7) | 19 (39.6) | 18 (41.9) | 21 (42.9) | 17 (41.5) | ||||||
x/x | 35 (36.1) | 21 (25.0) | 25 (52.1) | 16 (37.2) | 10 (20.4) | 5 (12.2) | ||||||
Missing | 3 | 9 | 2 | 6 | 1 | 3 | ||||||
IGFBP3 genotype | ||||||||||||
AA | 18 (18.0) | 23 (25.0) | 9 (18.0) | 15 (31.3) | 9 (18.0) | 8 (18.2) | ||||||
AC | 55 (55.0) | 41 (44.6) | 30 (60.0) | 21 (43.8) | 25 (50.0) | 20 (45.5) | ||||||
CC | 27 (27.0) | 28 (30.4) | 11 (22.0) | 12 (25.0) | 16 (32.0) | 16 (36.4) | ||||||
Missing | 1 | 1 |
. | Overall . | . | Blacks . | . | Whites . | . | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
. | Cases, n = 100 (%) . | Controls, n = 93 (%) . | Cases, n = 50 (%) . | Controls, n = 49 (%) . | Cases, n = 50 (%) . | Controls, n = 44 (%) . | ||||||
IGF1 CA repeat allele frequencies* | ||||||||||||
(CA)11 | 0 (0.0) | 1 (0.6) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (1.2) | ||||||
(CA)16 | 2 (1.0) | 9 (5.4) | 2 (2.1) | 9 (10.5) | 0 (0.0) | 0 (0.0) | ||||||
(CA)17 | 8 (4.1) | 5 (3.0) | 5 (5.2) | 3 (3.5) | 3 (3.1) | 2 (2.4) | ||||||
(CA)18 | 39 (20.1) | 23 (13.7) | 34 (35.4) | 17 (19.8) | 5 (5.1) | 6 (7.3) | ||||||
(CA)19 | 84 (43.3) | 91 (54.2) | 27 (28.1) | 36 (41.9) | 57 (58.2) | 55 (67.1) | ||||||
(CA)20 | 41 (21.1) | 24 (14.3) | 14 (14.6) | 10 (11.6) | 27 (27.6) | 14 (17.1) | ||||||
(CA)21 | 15 (7.7) | 12 (7.1) | 12 (12.5) | 9 (10.5) | 3 (3.1) | 3 (3.7) | ||||||
(CA)22 | 3 (1.6) | 2 (1.2) | 0 (0.0) | 1 (1.2) | 3 (3.1) | 1 (1.2) | ||||||
(CA)24 | 2 (1.0) | 1 (0.6) | 2 (2.1) | 1 (1.2) | 0 (0.0) | 0 (0.0) | ||||||
Missing | 6 | 18 | 4 | 12 | 2 | 6 | ||||||
IGF1 CA repeat genotype | ||||||||||||
(CA)19/(CA)19 | 22 (22.7) | 28 (33.3) | 4 (8.3) | 9 (20.9) | 18 (36.7) | 19 (46.3) | ||||||
(CA)19/x | 40 (41.2) | 35 (41.7) | 19 (39.6) | 18 (41.9) | 21 (42.9) | 17 (41.5) | ||||||
x/x | 35 (36.1) | 21 (25.0) | 25 (52.1) | 16 (37.2) | 10 (20.4) | 5 (12.2) | ||||||
Missing | 3 | 9 | 2 | 6 | 1 | 3 | ||||||
IGFBP3 genotype | ||||||||||||
AA | 18 (18.0) | 23 (25.0) | 9 (18.0) | 15 (31.3) | 9 (18.0) | 8 (18.2) | ||||||
AC | 55 (55.0) | 41 (44.6) | 30 (60.0) | 21 (43.8) | 25 (50.0) | 20 (45.5) | ||||||
CC | 27 (27.0) | 28 (30.4) | 11 (22.0) | 12 (25.0) | 16 (32.0) | 16 (36.4) | ||||||
Missing | 1 | 1 |
NOTE: x, non-(CA)19 repeat allele.
n is for alleles (two/person) rather than subjects.