Twinning rates among brothers and sisters of patients with testicular cancer
Type of delivery . | Siblings of patients with testicular cancer . | Controls . | OR (95% CI)* . | Born <1990 . | Born in 1990+ . | |||||
---|---|---|---|---|---|---|---|---|---|---|
Men | ||||||||||
Singleton (no.) | 4,339 | 5,088 | 1.00 | 1.00 | 1.00 | |||||
Unlike-sex twins | 11 | 23 | 0.53 (0.26-1.09) | 0.61 (0.21-1.80) | 0.48 (0.18-1.26) | |||||
Same-sex twins | 33 | 37 | 1.00 (0.62-1.60) | 1.08 (0.57-2.08) | 0.90 (0.45-1.79) | |||||
Unlike-sex twinning rate (per 1,000 births) | 2.5 | 4.5 | ||||||||
Women | ||||||||||
Singleton | 4,915 | 5,417 | 1.00 | 1.00 | 1.00 | |||||
Unlike-sex twins | 19 | 14 | 1.41 (0.70-2.82) | 1.55 (0.49-4.90) | 1.35 (0.57-3.23) | |||||
Same-sex twins | 50 | 42 | 1.27 (0.84-1.92) | 1.24 (0.73-2.11) | 1.34 (0.69-2.57) | |||||
Unlike-sex twinning rate (per 1,000 births) | 3.8 | 2.6 |
Type of delivery . | Siblings of patients with testicular cancer . | Controls . | OR (95% CI)* . | Born <1990 . | Born in 1990+ . | |||||
---|---|---|---|---|---|---|---|---|---|---|
Men | ||||||||||
Singleton (no.) | 4,339 | 5,088 | 1.00 | 1.00 | 1.00 | |||||
Unlike-sex twins | 11 | 23 | 0.53 (0.26-1.09) | 0.61 (0.21-1.80) | 0.48 (0.18-1.26) | |||||
Same-sex twins | 33 | 37 | 1.00 (0.62-1.60) | 1.08 (0.57-2.08) | 0.90 (0.45-1.79) | |||||
Unlike-sex twinning rate (per 1,000 births) | 2.5 | 4.5 | ||||||||
Women | ||||||||||
Singleton | 4,915 | 5,417 | 1.00 | 1.00 | 1.00 | |||||
Unlike-sex twins | 19 | 14 | 1.41 (0.70-2.82) | 1.55 (0.49-4.90) | 1.35 (0.57-3.23) | |||||
Same-sex twins | 50 | 42 | 1.27 (0.84-1.92) | 1.24 (0.73-2.11) | 1.34 (0.69-2.57) | |||||
Unlike-sex twinning rate (per 1,000 births) | 3.8 | 2.6 |
OR adjusted by year of birth (continuous), parental age (continuous), and birth order (1, 2, 3+).