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Table 3.

Family migration history and breast cancer risk in Hispanic women, by menopausal status

Premenopausal women
Postmenopausal women
Cases (n = 376)Controls (n = 482)Age-adjusted OR (95% CI)Cases (n = 615)Controls (n = 803)Age-adjusted OR (95% CI)
Generation       
    Third or higher 101 75 1.0 133 102 1.0 
    Second 73 68 0.80 (0.51-1.24) 188 175 0.82 (0.59-1.14) 
    First 200 336 0.45 (0.32-0.64) 289 522 0.42 (0.32-0.57) 
   Ptrend < 0.01   Ptrend < 0.01 
Birthplace of subject, birthplace of parents       
    United States, 2 United States 101 75 1.0 133 102 1.0 
    United States, 1 United States 50 33 1.11 (0.65-1.90) 70 70 0.78 (0.50-1.17) 
    United States, 2 foreign 23 33 0.52 (0.28-0.96) 117 104 0.86 (0.59-1.26) 
    Foreign, 1-2 United States 12 0.35 (0.13-0.98) 22 23 0.73 (0.39-1.39) 
    Foreign, 2 foreign 194 324 0.45 (0.32-0.64) 264 498 0.41 (0.30-0.55) 
Birthplace of subject, birthplace of grandparents       
    United States, 3-4 United States 40 32 1.0 94 51 1.0 
    United States, 1-2 United States 51 31 1.32 (0.69-2.52) 62 45 0.75 (0.45-1.26) 
    United States, 4 foreign 55 54 0.79 (0.43-1.43) 132 135 0.53 (0.35-0.80) 
    Foreign, 1-4 United States 21 18 0.95 (0.43-2.08) 47 51 0.50 (0.30-0.85) 
    Foreign, 4 foreign 174 314 0.44 (0.27-0.73) 228 460 0.27 (0.19-0.39) 
Birthplace of subject, birthplace of grandparents, type of residence before migration, years of U.S. residence*       
    Foreign, 4 foreign, rural, <20 y 20 61 0.27 (0.14-0.54) 14 46 0.17 (0.09-0.34) 
    Foreign, 4 foreign, mixed, <20 y 25 56 0.38 (0.19-0.74) 18 50 0.20 (0.11-0.38) 
    Foreign, 4 foreign, urban, <20 y 39 70 0.46 (0.25-0.86) 18 53 0.19 (0.10-0.36) 
    Foreign, 4 foreign, rural, ≥20 y 26 38 0.53 (0.27-1.07) 52 84 0.34 (0.21-0.56) 
    Foreign, 4 foreign, mixed, ≥20 y 11 18 0.46 (0.19-1.12) 37 78 0.26 (0.16-0.45) 
    Foreign, 4 foreign, urban, ≥20 y 41 39 0.83 (0.44-1.59) 68 111 0.34 (0.22-0.54) 
    Foreign, <4 foreign 17 13 1.11 (0.46-2.63) 39 45 0.48 (0.28-0.84) 
    United States, 4 foreign 51 51 0.79 (0.43-1.46) 125 116 0.60 (0.39-0.92) 
    United States, 1-2 United States 50 30 1.36 (0.71-2.63) 59 42 0.78 (0.46-1.32) 
    United States, 3-4 United States 38 31 1.0 90 50 1.0 
Premenopausal women
Postmenopausal women
Cases (n = 376)Controls (n = 482)Age-adjusted OR (95% CI)Cases (n = 615)Controls (n = 803)Age-adjusted OR (95% CI)
Generation       
    Third or higher 101 75 1.0 133 102 1.0 
    Second 73 68 0.80 (0.51-1.24) 188 175 0.82 (0.59-1.14) 
    First 200 336 0.45 (0.32-0.64) 289 522 0.42 (0.32-0.57) 
   Ptrend < 0.01   Ptrend < 0.01 
Birthplace of subject, birthplace of parents       
    United States, 2 United States 101 75 1.0 133 102 1.0 
    United States, 1 United States 50 33 1.11 (0.65-1.90) 70 70 0.78 (0.50-1.17) 
    United States, 2 foreign 23 33 0.52 (0.28-0.96) 117 104 0.86 (0.59-1.26) 
    Foreign, 1-2 United States 12 0.35 (0.13-0.98) 22 23 0.73 (0.39-1.39) 
    Foreign, 2 foreign 194 324 0.45 (0.32-0.64) 264 498 0.41 (0.30-0.55) 
Birthplace of subject, birthplace of grandparents       
    United States, 3-4 United States 40 32 1.0 94 51 1.0 
    United States, 1-2 United States 51 31 1.32 (0.69-2.52) 62 45 0.75 (0.45-1.26) 
    United States, 4 foreign 55 54 0.79 (0.43-1.43) 132 135 0.53 (0.35-0.80) 
    Foreign, 1-4 United States 21 18 0.95 (0.43-2.08) 47 51 0.50 (0.30-0.85) 
    Foreign, 4 foreign 174 314 0.44 (0.27-0.73) 228 460 0.27 (0.19-0.39) 
Birthplace of subject, birthplace of grandparents, type of residence before migration, years of U.S. residence*       
    Foreign, 4 foreign, rural, <20 y 20 61 0.27 (0.14-0.54) 14 46 0.17 (0.09-0.34) 
    Foreign, 4 foreign, mixed, <20 y 25 56 0.38 (0.19-0.74) 18 50 0.20 (0.11-0.38) 
    Foreign, 4 foreign, urban, <20 y 39 70 0.46 (0.25-0.86) 18 53 0.19 (0.10-0.36) 
    Foreign, 4 foreign, rural, ≥20 y 26 38 0.53 (0.27-1.07) 52 84 0.34 (0.21-0.56) 
    Foreign, 4 foreign, mixed, ≥20 y 11 18 0.46 (0.19-1.12) 37 78 0.26 (0.16-0.45) 
    Foreign, 4 foreign, urban, ≥20 y 41 39 0.83 (0.44-1.59) 68 111 0.34 (0.22-0.54) 
    Foreign, <4 foreign 17 13 1.11 (0.46-2.63) 39 45 0.48 (0.28-0.84) 
    United States, 4 foreign 51 51 0.79 (0.43-1.46) 125 116 0.60 (0.39-0.92) 
    United States, 1-2 United States 50 30 1.36 (0.71-2.63) 59 42 0.78 (0.46-1.32) 
    United States, 3-4 United States 38 31 1.0 90 50 1.0 
*

Excludes women with multiple moves between United States and foreign countries.

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