Family migration history and breast cancer risk in Hispanic women, by menopausal status
. | Premenopausal women . | . | . | Postmenopausal women . | . | . | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
. | Cases (n = 376) . | Controls (n = 482) . | Age-adjusted OR (95% CI) . | Cases (n = 615) . | Controls (n = 803) . | Age-adjusted OR (95% CI) . | ||||||
Generation | ||||||||||||
Third or higher | 101 | 75 | 1.0 | 133 | 102 | 1.0 | ||||||
Second | 73 | 68 | 0.80 (0.51-1.24) | 188 | 175 | 0.82 (0.59-1.14) | ||||||
First | 200 | 336 | 0.45 (0.32-0.64) | 289 | 522 | 0.42 (0.32-0.57) | ||||||
Ptrend < 0.01 | Ptrend < 0.01 | |||||||||||
Birthplace of subject, birthplace of parents | ||||||||||||
United States, 2 United States | 101 | 75 | 1.0 | 133 | 102 | 1.0 | ||||||
United States, 1 United States | 50 | 33 | 1.11 (0.65-1.90) | 70 | 70 | 0.78 (0.50-1.17) | ||||||
United States, 2 foreign | 23 | 33 | 0.52 (0.28-0.96) | 117 | 104 | 0.86 (0.59-1.26) | ||||||
Foreign, 1-2 United States | 6 | 12 | 0.35 (0.13-0.98) | 22 | 23 | 0.73 (0.39-1.39) | ||||||
Foreign, 2 foreign | 194 | 324 | 0.45 (0.32-0.64) | 264 | 498 | 0.41 (0.30-0.55) | ||||||
Birthplace of subject, birthplace of grandparents | ||||||||||||
United States, 3-4 United States | 40 | 32 | 1.0 | 94 | 51 | 1.0 | ||||||
United States, 1-2 United States | 51 | 31 | 1.32 (0.69-2.52) | 62 | 45 | 0.75 (0.45-1.26) | ||||||
United States, 4 foreign | 55 | 54 | 0.79 (0.43-1.43) | 132 | 135 | 0.53 (0.35-0.80) | ||||||
Foreign, 1-4 United States | 21 | 18 | 0.95 (0.43-2.08) | 47 | 51 | 0.50 (0.30-0.85) | ||||||
Foreign, 4 foreign | 174 | 314 | 0.44 (0.27-0.73) | 228 | 460 | 0.27 (0.19-0.39) | ||||||
Birthplace of subject, birthplace of grandparents, type of residence before migration, years of U.S. residence* | ||||||||||||
Foreign, 4 foreign, rural, <20 y | 20 | 61 | 0.27 (0.14-0.54) | 14 | 46 | 0.17 (0.09-0.34) | ||||||
Foreign, 4 foreign, mixed, <20 y | 25 | 56 | 0.38 (0.19-0.74) | 18 | 50 | 0.20 (0.11-0.38) | ||||||
Foreign, 4 foreign, urban, <20 y | 39 | 70 | 0.46 (0.25-0.86) | 18 | 53 | 0.19 (0.10-0.36) | ||||||
Foreign, 4 foreign, rural, ≥20 y | 26 | 38 | 0.53 (0.27-1.07) | 52 | 84 | 0.34 (0.21-0.56) | ||||||
Foreign, 4 foreign, mixed, ≥20 y | 11 | 18 | 0.46 (0.19-1.12) | 37 | 78 | 0.26 (0.16-0.45) | ||||||
Foreign, 4 foreign, urban, ≥20 y | 41 | 39 | 0.83 (0.44-1.59) | 68 | 111 | 0.34 (0.22-0.54) | ||||||
Foreign, <4 foreign | 17 | 13 | 1.11 (0.46-2.63) | 39 | 45 | 0.48 (0.28-0.84) | ||||||
United States, 4 foreign | 51 | 51 | 0.79 (0.43-1.46) | 125 | 116 | 0.60 (0.39-0.92) | ||||||
United States, 1-2 United States | 50 | 30 | 1.36 (0.71-2.63) | 59 | 42 | 0.78 (0.46-1.32) | ||||||
United States, 3-4 United States | 38 | 31 | 1.0 | 90 | 50 | 1.0 |
. | Premenopausal women . | . | . | Postmenopausal women . | . | . | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
. | Cases (n = 376) . | Controls (n = 482) . | Age-adjusted OR (95% CI) . | Cases (n = 615) . | Controls (n = 803) . | Age-adjusted OR (95% CI) . | ||||||
Generation | ||||||||||||
Third or higher | 101 | 75 | 1.0 | 133 | 102 | 1.0 | ||||||
Second | 73 | 68 | 0.80 (0.51-1.24) | 188 | 175 | 0.82 (0.59-1.14) | ||||||
First | 200 | 336 | 0.45 (0.32-0.64) | 289 | 522 | 0.42 (0.32-0.57) | ||||||
Ptrend < 0.01 | Ptrend < 0.01 | |||||||||||
Birthplace of subject, birthplace of parents | ||||||||||||
United States, 2 United States | 101 | 75 | 1.0 | 133 | 102 | 1.0 | ||||||
United States, 1 United States | 50 | 33 | 1.11 (0.65-1.90) | 70 | 70 | 0.78 (0.50-1.17) | ||||||
United States, 2 foreign | 23 | 33 | 0.52 (0.28-0.96) | 117 | 104 | 0.86 (0.59-1.26) | ||||||
Foreign, 1-2 United States | 6 | 12 | 0.35 (0.13-0.98) | 22 | 23 | 0.73 (0.39-1.39) | ||||||
Foreign, 2 foreign | 194 | 324 | 0.45 (0.32-0.64) | 264 | 498 | 0.41 (0.30-0.55) | ||||||
Birthplace of subject, birthplace of grandparents | ||||||||||||
United States, 3-4 United States | 40 | 32 | 1.0 | 94 | 51 | 1.0 | ||||||
United States, 1-2 United States | 51 | 31 | 1.32 (0.69-2.52) | 62 | 45 | 0.75 (0.45-1.26) | ||||||
United States, 4 foreign | 55 | 54 | 0.79 (0.43-1.43) | 132 | 135 | 0.53 (0.35-0.80) | ||||||
Foreign, 1-4 United States | 21 | 18 | 0.95 (0.43-2.08) | 47 | 51 | 0.50 (0.30-0.85) | ||||||
Foreign, 4 foreign | 174 | 314 | 0.44 (0.27-0.73) | 228 | 460 | 0.27 (0.19-0.39) | ||||||
Birthplace of subject, birthplace of grandparents, type of residence before migration, years of U.S. residence* | ||||||||||||
Foreign, 4 foreign, rural, <20 y | 20 | 61 | 0.27 (0.14-0.54) | 14 | 46 | 0.17 (0.09-0.34) | ||||||
Foreign, 4 foreign, mixed, <20 y | 25 | 56 | 0.38 (0.19-0.74) | 18 | 50 | 0.20 (0.11-0.38) | ||||||
Foreign, 4 foreign, urban, <20 y | 39 | 70 | 0.46 (0.25-0.86) | 18 | 53 | 0.19 (0.10-0.36) | ||||||
Foreign, 4 foreign, rural, ≥20 y | 26 | 38 | 0.53 (0.27-1.07) | 52 | 84 | 0.34 (0.21-0.56) | ||||||
Foreign, 4 foreign, mixed, ≥20 y | 11 | 18 | 0.46 (0.19-1.12) | 37 | 78 | 0.26 (0.16-0.45) | ||||||
Foreign, 4 foreign, urban, ≥20 y | 41 | 39 | 0.83 (0.44-1.59) | 68 | 111 | 0.34 (0.22-0.54) | ||||||
Foreign, <4 foreign | 17 | 13 | 1.11 (0.46-2.63) | 39 | 45 | 0.48 (0.28-0.84) | ||||||
United States, 4 foreign | 51 | 51 | 0.79 (0.43-1.46) | 125 | 116 | 0.60 (0.39-0.92) | ||||||
United States, 1-2 United States | 50 | 30 | 1.36 (0.71-2.63) | 59 | 42 | 0.78 (0.46-1.32) | ||||||
United States, 3-4 United States | 38 | 31 | 1.0 | 90 | 50 | 1.0 |
Excludes women with multiple moves between United States and foreign countries.