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Table 2.

Birthplace, timing of migration to the United States, and breast cancer risk in Hispanic women, by menopausal status

Premenopausal women
Postmenopausal women
Cases (n = 376)Controls (n = 482)Age-adjusted OR (95% CI)Cases (n = 615)Controls (n = 803)Age-adjusted OR (95% CI)
Place of birth       
    United States* 176 146 1.0 326 281 1.0 
    Foreign 200 336 0.50 (0.38-0.67) 289 522 0.48 (0.38-0.59) 
        Mexico 117 225 0.44 (0.32-0.60) 144 300 0.41 (0.32-0.53) 
        Central America 50 81 0.52 (0.34-0.78) 86 165 0.45 (0.33-0.61) 
        Cuba, Puerto Rico, Dominican Republic 11 0.61 (0.24-1.57) 20 18 0.96 (0.50-1.85) 
        South America 24 17 1.26 (0.65-2.45) 33 38 0.75 (0.46-1.22) 
    Other 0.44 (0.04-4.99) 5.16 (0.62-43.14) 
Type of residence before migration       
    U.S.-born 176 146 1.0 326 281 1.0 
    Urban 104 135 0.65 (0.46-0.91) 134 226 0.51 (0.39-0.67) 
    Mixed urban and rural 43 82 0.45 (0.29-0.69) 78 154 0.44 (0.32-0.60) 
    Rural 53 116 0.38 (0.26-0.56) 76 141 0.46 (0.34-0.64) 
Years of residence in the United States*,,       
    U.S.-born 166 140 1.0 311 255 1.0 
    ≥40 1.17 (0.41-3.38) 82 103 0.66 (0.47-0.92) 
    30-39 25 20 0.99 (0.52-1.87) 77 115 0.55 (0.39-0.76) 
    20-29 57 77 0.62 (0.41-0.94) 40 98 0.33 (0.22-0.50) 
    10-19 66 134 0.43 (0.30-0.62) 35 93 0.31 (0.20-0.47) 
    <10 25 65 0.34 (0.20-0.57) 23 68 0.28 (0.17-0.46) 
   Ptrend < 0.01   Ptrend < 0.01 
% of Life spent in the United States*,,       
    100% (U.S.-born) 166 140 1.0 311 255 1.0 
    75-99% 21 14 1.27 (0.62-2.60) 37 41 0.74 (0.46-1.19) 
    50-74% 56 75 0.62 (0.41-0.94) 113 180 0.52 (0.39-0.69) 
    25-49% 72 141 0.45 (0.31-0.65) 65 143 0.37 (0.27-0.52) 
    <25% 33 72 0.39 (0.25-0.63) 42 113 0.31 (0.21-0.45) 
   Ptrend < 0.01   Ptrend < 0.01 
Age at migration to the United States*,       
    U.S.-born 166 140 1.0 311 255 1.0 
    <10 17 13 1.14 (0.53-2.43) 19 20 0.79 (0.41-1.51) 
    10-19 47 58 0.72 (0.46-1.13) 48 58 0.69 (0.45-1.05) 
    20-29 64 121 0.48 (0.33-0.71) 74 141 0.44 (0.31-0.61) 
    30-39 44 90 0.40 (0.26-0.62) 48 96 0.42 (0.28-0.61) 
    ≥40 10 20 0.35 (0.16-0.78) 68 162 0.34 (0.25-0.48) 
   Ptrend < 0.01   Ptrend < 0.01 
Premenopausal women
Postmenopausal women
Cases (n = 376)Controls (n = 482)Age-adjusted OR (95% CI)Cases (n = 615)Controls (n = 803)Age-adjusted OR (95% CI)
Place of birth       
    United States* 176 146 1.0 326 281 1.0 
    Foreign 200 336 0.50 (0.38-0.67) 289 522 0.48 (0.38-0.59) 
        Mexico 117 225 0.44 (0.32-0.60) 144 300 0.41 (0.32-0.53) 
        Central America 50 81 0.52 (0.34-0.78) 86 165 0.45 (0.33-0.61) 
        Cuba, Puerto Rico, Dominican Republic 11 0.61 (0.24-1.57) 20 18 0.96 (0.50-1.85) 
        South America 24 17 1.26 (0.65-2.45) 33 38 0.75 (0.46-1.22) 
    Other 0.44 (0.04-4.99) 5.16 (0.62-43.14) 
Type of residence before migration       
    U.S.-born 176 146 1.0 326 281 1.0 
    Urban 104 135 0.65 (0.46-0.91) 134 226 0.51 (0.39-0.67) 
    Mixed urban and rural 43 82 0.45 (0.29-0.69) 78 154 0.44 (0.32-0.60) 
    Rural 53 116 0.38 (0.26-0.56) 76 141 0.46 (0.34-0.64) 
Years of residence in the United States*,,       
    U.S.-born 166 140 1.0 311 255 1.0 
    ≥40 1.17 (0.41-3.38) 82 103 0.66 (0.47-0.92) 
    30-39 25 20 0.99 (0.52-1.87) 77 115 0.55 (0.39-0.76) 
    20-29 57 77 0.62 (0.41-0.94) 40 98 0.33 (0.22-0.50) 
    10-19 66 134 0.43 (0.30-0.62) 35 93 0.31 (0.20-0.47) 
    <10 25 65 0.34 (0.20-0.57) 23 68 0.28 (0.17-0.46) 
   Ptrend < 0.01   Ptrend < 0.01 
% of Life spent in the United States*,,       
    100% (U.S.-born) 166 140 1.0 311 255 1.0 
    75-99% 21 14 1.27 (0.62-2.60) 37 41 0.74 (0.46-1.19) 
    50-74% 56 75 0.62 (0.41-0.94) 113 180 0.52 (0.39-0.69) 
    25-49% 72 141 0.45 (0.31-0.65) 65 143 0.37 (0.27-0.52) 
    <25% 33 72 0.39 (0.25-0.63) 42 113 0.31 (0.21-0.45) 
   Ptrend < 0.01   Ptrend < 0.01 
Age at migration to the United States*,       
    U.S.-born 166 140 1.0 311 255 1.0 
    <10 17 13 1.14 (0.53-2.43) 19 20 0.79 (0.41-1.51) 
    10-19 47 58 0.72 (0.46-1.13) 48 58 0.69 (0.45-1.05) 
    20-29 64 121 0.48 (0.33-0.71) 74 141 0.44 (0.31-0.61) 
    30-39 44 90 0.40 (0.26-0.62) 48 96 0.42 (0.28-0.61) 
    ≥40 10 20 0.35 (0.16-0.78) 68 162 0.34 (0.25-0.48) 
   Ptrend < 0.01   Ptrend < 0.01 
*

U.S.-born reference group includes women born in the United States or other Western countries (i.e., Canada, Europe, Australia, and New Zealand).

Excludes women with two or more lifetime moves between the United States and foreign countries.

Includes time spent in United States and other Western countries.

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