IRRs of second primary cancer according to XPD genotype and cigarette smoking status in a cohort of individuals with a history of NMSC, Washington County, Maryland, 1989 to 2002
| Smoking status* . | XPD genotypes . | Developed second primary cancer . | . | Incident cases per 100 person-years . | Multivariate adjusted IRR (95% CI)† . | |
|---|---|---|---|---|---|---|
| . | . | Yes, n (%) . | No, n (%) . | . | . | |
| Never | Lys/Lys | 4 (5.0) | 83 (20.7) | 0.40 | 1.00 (reference) | |
| Lys/Gln and Gln/Gln | 24 (30.0) | 119 (29.7) | 1.52 | 3.93 (1.36-11.36) | ||
| Ever | Lys/Lys | 14 (17.5) | 77 (19.3) | 1.42 | 3.51 (1.14-10.80) | |
| Lys/Gln and Gln/Gln | 38 (47.5) | 121 (30.3) | 2.30 | 6.14 (2.17-17.37) | ||
| Smoking status* . | XPD genotypes . | Developed second primary cancer . | . | Incident cases per 100 person-years . | Multivariate adjusted IRR (95% CI)† . | |
|---|---|---|---|---|---|---|
| . | . | Yes, n (%) . | No, n (%) . | . | . | |
| Never | Lys/Lys | 4 (5.0) | 83 (20.7) | 0.40 | 1.00 (reference) | |
| Lys/Gln and Gln/Gln | 24 (30.0) | 119 (29.7) | 1.52 | 3.93 (1.36-11.36) | ||
| Ever | Lys/Lys | 14 (17.5) | 77 (19.3) | 1.42 | 3.51 (1.14-10.80) | |
| Lys/Gln and Gln/Gln | 38 (47.5) | 121 (30.3) | 2.30 | 6.14 (2.17-17.37) | ||