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Table 1.

Relative risks comparing the top quantile versus the bottom quantile and 95% CIs from cohort studies and clinical trials examining the role of dietary fiber and colorectal neoplasia by type of fiber and disease type

Study authorFiber source (Relative risk comparing the top quantile vs the bottom quantile and 95% CI)
Total fiberCereal fiberVegetable fiberFruit fiberLegume fiberSoluble fiberInsoluble fiber
Bingham et al. (12)        
    Colorectal cancer 0.75 (0.59-0.95) 0.78 (0.62-0.98) 0.88 (0.70-1.11) 0.78 (0.64-0.97) 1.04 (0.84-1.30)   
Peters et al. (13)        
    Distal colorectal adenomas 0.91 (0.86-0.97) 0.88 (0.79-0.97) 1.00 (0.89-1.15) 0.80 (0.71-0.93) 0.99 (0.78-1.20)   
Mai et al. (8)        
    Colorectal cancer 0.94 (0.70-1.26) 1.02 (0.76-1.37) 0.92 (0.69-1.21) 1.10 (0.83-1.46) 0.84 (0.63-1.10)   
Jacobs et al. (7)        
    Recurrent colorectal adenomas 0.83 (0.57-1.19) 0.84 (0.59-1.19) 1.34 (0.94-1.91) 0.92 (0.64-1.32)    
Terry et al. (5)        
    Colorectal cancer 0.96 (0.70-1.33) 0.91 (0.69-1.20) 1.17 (0.85-1.61) 0.97 (0.69-1.38)    
    Colon cancer  0.84 (0.59-1.20)      
    Proximal colon cancer  0.77 (0.45-1.32)      
    Distal colon cancer  0.86 (0.47-1.60)      
    Rectal cancer  1.10 (0.69-1.76)      
Fuchs et al. (4)        
    Colorectal cancer 0.95 (0.73-1.25) 1.00 (0.79-1.27) 1.35 (1.05-1.72) 0.86 (0.67-1.10)    
    Distal colorectal adenomas 0.91 (0.71-1.16) 0.92 (0.75-1.14) 0.89 (0.71-1.12) 0.85 (0.68-1.06)    
Pietinen et al. (6)        
    Colorectal cancer 1.00 (0.6-1.5) 1.00 (0.7-1.6) 1.2 (0.8-1.9) 1.10 (0.8-1.7)  1.1 (0.7-1.6) 1.0 (0.6-1.5) 
Platz et al. (3)        
    Distal colon adenomas  0.88 (0.59-1.31) 1.20 (0.86-1.66) 0.93 (0.67-1.30) 0.81 (0.59-1.11) 0.82 (0.60-1.11) 0.69 (0.46-1.03) 1.14 (0.77-1.69) 
Study authorFiber source (Relative risk comparing the top quantile vs the bottom quantile and 95% CI)
Total fiberCereal fiberVegetable fiberFruit fiberLegume fiberSoluble fiberInsoluble fiber
Bingham et al. (12)        
    Colorectal cancer 0.75 (0.59-0.95) 0.78 (0.62-0.98) 0.88 (0.70-1.11) 0.78 (0.64-0.97) 1.04 (0.84-1.30)   
Peters et al. (13)        
    Distal colorectal adenomas 0.91 (0.86-0.97) 0.88 (0.79-0.97) 1.00 (0.89-1.15) 0.80 (0.71-0.93) 0.99 (0.78-1.20)   
Mai et al. (8)        
    Colorectal cancer 0.94 (0.70-1.26) 1.02 (0.76-1.37) 0.92 (0.69-1.21) 1.10 (0.83-1.46) 0.84 (0.63-1.10)   
Jacobs et al. (7)        
    Recurrent colorectal adenomas 0.83 (0.57-1.19) 0.84 (0.59-1.19) 1.34 (0.94-1.91) 0.92 (0.64-1.32)    
Terry et al. (5)        
    Colorectal cancer 0.96 (0.70-1.33) 0.91 (0.69-1.20) 1.17 (0.85-1.61) 0.97 (0.69-1.38)    
    Colon cancer  0.84 (0.59-1.20)      
    Proximal colon cancer  0.77 (0.45-1.32)      
    Distal colon cancer  0.86 (0.47-1.60)      
    Rectal cancer  1.10 (0.69-1.76)      
Fuchs et al. (4)        
    Colorectal cancer 0.95 (0.73-1.25) 1.00 (0.79-1.27) 1.35 (1.05-1.72) 0.86 (0.67-1.10)    
    Distal colorectal adenomas 0.91 (0.71-1.16) 0.92 (0.75-1.14) 0.89 (0.71-1.12) 0.85 (0.68-1.06)    
Pietinen et al. (6)        
    Colorectal cancer 1.00 (0.6-1.5) 1.00 (0.7-1.6) 1.2 (0.8-1.9) 1.10 (0.8-1.7)  1.1 (0.7-1.6) 1.0 (0.6-1.5) 
Platz et al. (3)        
    Distal colon adenomas  0.88 (0.59-1.31) 1.20 (0.86-1.66) 0.93 (0.67-1.30) 0.81 (0.59-1.11) 0.82 (0.60-1.11) 0.69 (0.46-1.03) 1.14 (0.77-1.69) 
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