Relative risks comparing the top quantile versus the bottom quantile and 95% CIs from cohort studies and clinical trials examining the role of dietary fiber and colorectal neoplasia by type of fiber and disease type
| Study author . | Fiber source (Relative risk comparing the top quantile vs the bottom quantile and 95% CI) . | . | . | . | . | . | . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | Total fiber . | Cereal fiber . | Vegetable fiber . | Fruit fiber . | Legume fiber . | Soluble fiber . | Insoluble fiber . | |||||||
| Bingham et al. (12) | ||||||||||||||
| Colorectal cancer | 0.75 (0.59-0.95) | 0.78 (0.62-0.98) | 0.88 (0.70-1.11) | 0.78 (0.64-0.97) | 1.04 (0.84-1.30) | |||||||||
| Peters et al. (13) | ||||||||||||||
| Distal colorectal adenomas | 0.91 (0.86-0.97) | 0.88 (0.79-0.97) | 1.00 (0.89-1.15) | 0.80 (0.71-0.93) | 0.99 (0.78-1.20) | |||||||||
| Mai et al. (8) | ||||||||||||||
| Colorectal cancer | 0.94 (0.70-1.26) | 1.02 (0.76-1.37) | 0.92 (0.69-1.21) | 1.10 (0.83-1.46) | 0.84 (0.63-1.10) | |||||||||
| Jacobs et al. (7) | ||||||||||||||
| Recurrent colorectal adenomas | 0.83 (0.57-1.19) | 0.84 (0.59-1.19) | 1.34 (0.94-1.91) | 0.92 (0.64-1.32) | ||||||||||
| Terry et al. (5) | ||||||||||||||
| Colorectal cancer | 0.96 (0.70-1.33) | 0.91 (0.69-1.20) | 1.17 (0.85-1.61) | 0.97 (0.69-1.38) | ||||||||||
| Colon cancer | 0.84 (0.59-1.20) | |||||||||||||
| Proximal colon cancer | 0.77 (0.45-1.32) | |||||||||||||
| Distal colon cancer | 0.86 (0.47-1.60) | |||||||||||||
| Rectal cancer | 1.10 (0.69-1.76) | |||||||||||||
| Fuchs et al. (4) | ||||||||||||||
| Colorectal cancer | 0.95 (0.73-1.25) | 1.00 (0.79-1.27) | 1.35 (1.05-1.72) | 0.86 (0.67-1.10) | ||||||||||
| Distal colorectal adenomas | 0.91 (0.71-1.16) | 0.92 (0.75-1.14) | 0.89 (0.71-1.12) | 0.85 (0.68-1.06) | ||||||||||
| Pietinen et al. (6) | ||||||||||||||
| Colorectal cancer | 1.00 (0.6-1.5) | 1.00 (0.7-1.6) | 1.2 (0.8-1.9) | 1.10 (0.8-1.7) | 1.1 (0.7-1.6) | 1.0 (0.6-1.5) | ||||||||
| Platz et al. (3) | ||||||||||||||
| Distal colon adenomas | 0.88 (0.59-1.31) | 1.20 (0.86-1.66) | 0.93 (0.67-1.30) | 0.81 (0.59-1.11) | 0.82 (0.60-1.11) | 0.69 (0.46-1.03) | 1.14 (0.77-1.69) | |||||||
| Study author . | Fiber source (Relative risk comparing the top quantile vs the bottom quantile and 95% CI) . | . | . | . | . | . | . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | Total fiber . | Cereal fiber . | Vegetable fiber . | Fruit fiber . | Legume fiber . | Soluble fiber . | Insoluble fiber . | |||||||
| Bingham et al. (12) | ||||||||||||||
| Colorectal cancer | 0.75 (0.59-0.95) | 0.78 (0.62-0.98) | 0.88 (0.70-1.11) | 0.78 (0.64-0.97) | 1.04 (0.84-1.30) | |||||||||
| Peters et al. (13) | ||||||||||||||
| Distal colorectal adenomas | 0.91 (0.86-0.97) | 0.88 (0.79-0.97) | 1.00 (0.89-1.15) | 0.80 (0.71-0.93) | 0.99 (0.78-1.20) | |||||||||
| Mai et al. (8) | ||||||||||||||
| Colorectal cancer | 0.94 (0.70-1.26) | 1.02 (0.76-1.37) | 0.92 (0.69-1.21) | 1.10 (0.83-1.46) | 0.84 (0.63-1.10) | |||||||||
| Jacobs et al. (7) | ||||||||||||||
| Recurrent colorectal adenomas | 0.83 (0.57-1.19) | 0.84 (0.59-1.19) | 1.34 (0.94-1.91) | 0.92 (0.64-1.32) | ||||||||||
| Terry et al. (5) | ||||||||||||||
| Colorectal cancer | 0.96 (0.70-1.33) | 0.91 (0.69-1.20) | 1.17 (0.85-1.61) | 0.97 (0.69-1.38) | ||||||||||
| Colon cancer | 0.84 (0.59-1.20) | |||||||||||||
| Proximal colon cancer | 0.77 (0.45-1.32) | |||||||||||||
| Distal colon cancer | 0.86 (0.47-1.60) | |||||||||||||
| Rectal cancer | 1.10 (0.69-1.76) | |||||||||||||
| Fuchs et al. (4) | ||||||||||||||
| Colorectal cancer | 0.95 (0.73-1.25) | 1.00 (0.79-1.27) | 1.35 (1.05-1.72) | 0.86 (0.67-1.10) | ||||||||||
| Distal colorectal adenomas | 0.91 (0.71-1.16) | 0.92 (0.75-1.14) | 0.89 (0.71-1.12) | 0.85 (0.68-1.06) | ||||||||||
| Pietinen et al. (6) | ||||||||||||||
| Colorectal cancer | 1.00 (0.6-1.5) | 1.00 (0.7-1.6) | 1.2 (0.8-1.9) | 1.10 (0.8-1.7) | 1.1 (0.7-1.6) | 1.0 (0.6-1.5) | ||||||||
| Platz et al. (3) | ||||||||||||||
| Distal colon adenomas | 0.88 (0.59-1.31) | 1.20 (0.86-1.66) | 0.93 (0.67-1.30) | 0.81 (0.59-1.11) | 0.82 (0.60-1.11) | 0.69 (0.46-1.03) | 1.14 (0.77-1.69) | |||||||