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Table 1.

Summary of nested case-control studies of C. pneumoniae and lung cancer risk with blood collected before lung cancer diagnosis in cases and a comparable time in controls

First author, year, locationPopulationNumber of subjectsTime between blood sampling and lung cancer diagnosis/censoring (y)Variables adjusted for in multivariate models
Laurila, 1997 (23), Finland Male smokers involved in a randomized trial of β-carotene and α-tocopherol 230 cases/230 controls 3-8 (median = 6.1) Years of smoking and cigarettes smoked per day 
Anttila, 2003 (28), Finland Women in 1st trimester of pregnancy in Finnish Maternity Cohort 58 cases/287 controls 1.6-16.7 (mean = 9.1) Current smoking defined by serum cotinine levels 
Littman, 2004 (29), USA Men and women involved in a randomized trial of β-carotene and retinol 508 cases/508 controls 0-16 (median = 9) Years of smoking, cigarettes smoked per day, education, and body mass index (kg/m2
First author, year, locationPopulationNumber of subjectsTime between blood sampling and lung cancer diagnosis/censoring (y)Variables adjusted for in multivariate models
Laurila, 1997 (23), Finland Male smokers involved in a randomized trial of β-carotene and α-tocopherol 230 cases/230 controls 3-8 (median = 6.1) Years of smoking and cigarettes smoked per day 
Anttila, 2003 (28), Finland Women in 1st trimester of pregnancy in Finnish Maternity Cohort 58 cases/287 controls 1.6-16.7 (mean = 9.1) Current smoking defined by serum cotinine levels 
Littman, 2004 (29), USA Men and women involved in a randomized trial of β-carotene and retinol 508 cases/508 controls 0-16 (median = 9) Years of smoking, cigarettes smoked per day, education, and body mass index (kg/m2
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