Comparison of cases and controls for demographic and selected breast cancer risk factors among subjects with genotype information, the Shanghai Breast Cancer Study
| Subject characteristics* . | Cases(n=1,130) . | Controls(n=1,196) . | P . | |||
|---|---|---|---|---|---|---|
| Demographic factors | ||||||
| Age(y) | 47.6±8.0 | 47.2±8.7 | 0.20 | |||
| Education(%high school or more) | 43.6 | 43.1 | 0.81 | |||
| Reproductive risk factors | ||||||
| Age at menarche | 14.5±1.6 | 14.7±1.7 | <0.01 | |||
| Age at menopause† | 48.2±4.7 | 47.4±5.0 | 0.03 | |||
| Age at first live birth‡ | 26.8±4.1 | 26.2±3.8 | <0.01 | |||
| Total years of menstruation | 29.8±5.1 | 28.5±5.5 | <0.01 | |||
| No. live births‡ | 1.48±0.81 | 1.52±0.86 | 0.24 | |||
| Other risk factors | ||||||
| Breast cancer among first degree relatives(%) | 3.4 | 2.4 | 0.14 | |||
| Ever had breast fibroadenoma(%) | 9.7 | 5.3 | <0.01 | |||
| Ever used hormone replacement therapy(%) | 2.5 | 2.5 | 0.97 | |||
| BMI (kg/m2) | 23.5 ± 3.4 | 23.2 ± 3.4 | 0.01 | |||
| WHR | 0.81 ± 0.06 | 0.80 ± 0.06 | <0.01 | |||
| Alcohol consumption(% ever) | 3.6 | 3.9 | 0.70 | |||
| Physically active during past 10 years(%) | 19.4 | 26.1 | <0.01 | |||
| Ever used oral contraceptive(%) | 21.4 | 21.5 | 0.97 | |||
| Subject characteristics* . | Cases(n=1,130) . | Controls(n=1,196) . | P . | |||
|---|---|---|---|---|---|---|
| Demographic factors | ||||||
| Age(y) | 47.6±8.0 | 47.2±8.7 | 0.20 | |||
| Education(%high school or more) | 43.6 | 43.1 | 0.81 | |||
| Reproductive risk factors | ||||||
| Age at menarche | 14.5±1.6 | 14.7±1.7 | <0.01 | |||
| Age at menopause† | 48.2±4.7 | 47.4±5.0 | 0.03 | |||
| Age at first live birth‡ | 26.8±4.1 | 26.2±3.8 | <0.01 | |||
| Total years of menstruation | 29.8±5.1 | 28.5±5.5 | <0.01 | |||
| No. live births‡ | 1.48±0.81 | 1.52±0.86 | 0.24 | |||
| Other risk factors | ||||||
| Breast cancer among first degree relatives(%) | 3.4 | 2.4 | 0.14 | |||
| Ever had breast fibroadenoma(%) | 9.7 | 5.3 | <0.01 | |||
| Ever used hormone replacement therapy(%) | 2.5 | 2.5 | 0.97 | |||
| BMI (kg/m2) | 23.5 ± 3.4 | 23.2 ± 3.4 | 0.01 | |||
| WHR | 0.81 ± 0.06 | 0.80 ± 0.06 | <0.01 | |||
| Alcohol consumption(% ever) | 3.6 | 3.9 | 0.70 | |||
| Physically active during past 10 years(%) | 19.4 | 26.1 | <0.01 | |||
| Ever used oral contraceptive(%) | 21.4 | 21.5 | 0.97 | |||