American Association for Cancer Research

Table 4.

Fat intakes and total specific types of fat (% calories) and risk for breast cancer in Mexican women

Range of intake (% Calories)	All women (n = 1,866)							Premenopausal women (n = 875)
Range of intake (% Calories)		Control	Cases	OR Age Adjusted (95% CI)	OR* (95% CI)	Controls	Cases	OR* (95% CI)	Controls	Cases	OR* (95% CI)
Total fat
≤24.1	348	171	1.00	1.00	181	64	1.00	167	107	1.00
2.2-27.9	347	102	0.57 (0.43-0.76)	0.70 (0.51-0.95)	168	42	0.91 (0.56-1.48)	179	60	0.58 (0.38-0.89)
28.0-32.1	348	98	0.57 (0.43-0.77)	0.73 (0.53-1.02)	172	43	1.04 (0.63-1.70)	176	55	0.55 (0.35-0.87)
>32.1	348	104	0.59 (0.44-0.78)	0.83 (0.59-1.16)	165	40	1.03 (0.61-1.74)	183	64	0.71 (0.45-1.12)
P for trend			0.000	0.361			0.784			0.171
Saturated fat^†
≤8.5	347	144	1.00	1.00	181	62	1.00	166	82	1.00
8.6-11.2	349	109	0.80 (0.58-1.11)	0.96 (0.68-1.36)	196	51	1.05 (0.62-1.80)	153	53	0.82 (0.51-1.31)
11.3-13.2	348	84	0.64 (0.43-0.96)	0.87 (0.56-1.34)	157	38	1.23 (0.63-2.41)	191	46	0.62 (0.34-1.11)
>13.2	347	138	0.89 (0.57-1.39)	1.37 (0.83-2.25)	152	38	1.34 (0.59-3.01)	195	100	1.15 (0.60-2.20)
P for trend			0.272	0.372			0.511			0.852
Monounsaturated fat^†
≤8.1	348	164	1.00	1.00	178	70	1.00	170	94	1.00
8.2-9.3	347	96	0.77 (0.54-1.09)	0.81 (0.56-1.17)	182	40	0.63 (0.35-1.11)	165	56	1.01 (0.61-1.66)
9.4-10.6	349	109	0.97 (0.64-1.48)	1.00 (0.65-1.55)	171	41	0.80 (0.41-1.55)	178	68	1.38 (0.75-2.53)
>10.6	347	106	1.05 (0.63-1.75)	1.13 (0.67-1.91)	155	38	0.88 (0.39-2.00)	192	68	1.56 (0.77-3.15)
P for trend			0.413	0.319			0.985			0.085
Polyunsaturated fat^†
≤2.7	348	176	1.00	1.00	196	62	1.00	152	114	1.00
2.8-3.1	347	131	0.78 (0.58-1.05)	0.86 (0.63-1.18)	169	50	1.02 (0.62-1.68)	178	81	0.71 (0.47-1.08)
3.2-3.6	349	97	0.57 (0.41-0.79)	0.68 (0.47-0.98)	168	46	0.87 (0.50-1.52)	181	51	0.51 (0.31-0.85)
>3.6	347	71	0.38 (0.26-0.56)	0.47 (0.31-0.72)	153	31	0.68 (0.36-1.30)	194	40	0.37 (0.20-0.66)
P for trend			0.000	<0.001			0.181			<0.001

Range of intake (% Calories)	All women (n = 1,866)							Premenopausal women (n = 875)
Range of intake (% Calories)		Control	Cases	OR Age Adjusted (95% CI)	OR* (95% CI)	Controls	Cases	OR* (95% CI)	Controls	Cases	OR* (95% CI)
Total fat
≤24.1	348	171	1.00	1.00	181	64	1.00	167	107	1.00
2.2-27.9	347	102	0.57 (0.43-0.76)	0.70 (0.51-0.95)	168	42	0.91 (0.56-1.48)	179	60	0.58 (0.38-0.89)
28.0-32.1	348	98	0.57 (0.43-0.77)	0.73 (0.53-1.02)	172	43	1.04 (0.63-1.70)	176	55	0.55 (0.35-0.87)
>32.1	348	104	0.59 (0.44-0.78)	0.83 (0.59-1.16)	165	40	1.03 (0.61-1.74)	183	64	0.71 (0.45-1.12)
P for trend			0.000	0.361			0.784			0.171
Saturated fat^†
≤8.5	347	144	1.00	1.00	181	62	1.00	166	82	1.00
8.6-11.2	349	109	0.80 (0.58-1.11)	0.96 (0.68-1.36)	196	51	1.05 (0.62-1.80)	153	53	0.82 (0.51-1.31)
11.3-13.2	348	84	0.64 (0.43-0.96)	0.87 (0.56-1.34)	157	38	1.23 (0.63-2.41)	191	46	0.62 (0.34-1.11)
>13.2	347	138	0.89 (0.57-1.39)	1.37 (0.83-2.25)	152	38	1.34 (0.59-3.01)	195	100	1.15 (0.60-2.20)
P for trend			0.272	0.372			0.511			0.852
Monounsaturated fat^†
≤8.1	348	164	1.00	1.00	178	70	1.00	170	94	1.00
8.2-9.3	347	96	0.77 (0.54-1.09)	0.81 (0.56-1.17)	182	40	0.63 (0.35-1.11)	165	56	1.01 (0.61-1.66)
9.4-10.6	349	109	0.97 (0.64-1.48)	1.00 (0.65-1.55)	171	41	0.80 (0.41-1.55)	178	68	1.38 (0.75-2.53)
>10.6	347	106	1.05 (0.63-1.75)	1.13 (0.67-1.91)	155	38	0.88 (0.39-2.00)	192	68	1.56 (0.77-3.15)
P for trend			0.413	0.319			0.985			0.085
Polyunsaturated fat^†
≤2.7	348	176	1.00	1.00	196	62	1.00	152	114	1.00
2.8-3.1	347	131	0.78 (0.58-1.05)	0.86 (0.63-1.18)	169	50	1.02 (0.62-1.68)	178	81	0.71 (0.47-1.08)
3.2-3.6	349	97	0.57 (0.41-0.79)	0.68 (0.47-0.98)	168	46	0.87 (0.50-1.52)	181	51	0.51 (0.31-0.85)
>3.6	347	71	0.38 (0.26-0.56)	0.47 (0.31-0.72)	153	31	0.68 (0.36-1.30)	194	40	0.37 (0.20-0.66)
P for trend			0.000	<0.001			0.181			<0.001

Adjusted for age, total energy intake, protein intake (% calories), SES, family breast cancer, menopausal status, and parity.

†

Saturated fat, monounsaturated fat, and polyunsaturated fat are all in the same models without total fat.

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