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Table 2.

Correlation matrix of urinary phytoestrogen excretion and serum phytoestrogen levels (n = 284–333)

Urinary excretion without (a) and with (b) adjustment for urinary creatinine concentration (ng/ml; μg/mmol creatinine)
Daidzein
Genistein
Glycitein
O-DMA
Equol
Isoflavones
Enterodiol
Enterolactone
Lignans
ababababababababab
Serum levels (ng/ml) Isoflavones 0.72* 0.84* 0.75* 0.88* 0.63* 0.76* 0.43* 0.47* 0.14 0.19 0.74* 0.85* 0.07 0.02 −0.03 −0.07 0.01 −0.04 
     Daidzein 0.800.910.69* 0.79* 0.64* 0.77* 0.46* 0.46* 0.11 0.15 0.76* 0.89* 0.05 0.03 0.01 −0.01 0.03 0.00 
     Genistein 0.66* 0.76* 0.76* 0.89* 0.60* 0.71* 0.35* 0.39* 0.13 0.18 0.70* 0.79* 0.06 
     Glycitein 0.61* 0.68* 0.62* 0.68* 0.680.810.36* 0.33* 0.10 0.11 0.61* 0.66* 0.12 0.05 −0.07 −0.16 −0.02 −0.12 
     O-DMA 0.36* 0.47* 0.26* 0.34* 0.27* 0.36* 0.66* 0.82* 0.04 0.06 0.36* 0.45* −0.02 −0.01 −0.02 −0.01 0.00 0.02 
     Equol 0.11 0.18 0.16 0.24* 0.08 0.15 0.18 0.22* 0.620.810.17 0.24* −0.04 −0.01 0.02 0.06 0.01 0.06 
 Lignans −0.02 0.03 −0.13 −0.10 −0.11 −0.09 0.04 0.05 0.03 0.05 −0.06 −0.02 0.37* 0.47* 0.77* 0.91* 0.76* 0.93* 
     Enterodiol 0.05 0.08 0.00 0.03 0.04 0.08 −0.01 0.01 0.02 0.04 0.04 0.07 0.670.830.23* 0.28* 0.33* 0.40* 
     Enterolactone −0.03 −0.01 −0.15 −0.13 −0.13 −0.13 0.02 0.01 0.02 0.03 −0.08 −0.06 0.27* 0.34* 0.810.940.75* 0.90* 
Urinary excretion without (a) and with (b) adjustment for urinary creatinine concentration (ng/ml; μg/mmol creatinine)
Daidzein
Genistein
Glycitein
O-DMA
Equol
Isoflavones
Enterodiol
Enterolactone
Lignans
ababababababababab
Serum levels (ng/ml) Isoflavones 0.72* 0.84* 0.75* 0.88* 0.63* 0.76* 0.43* 0.47* 0.14 0.19 0.74* 0.85* 0.07 0.02 −0.03 −0.07 0.01 −0.04 
     Daidzein 0.800.910.69* 0.79* 0.64* 0.77* 0.46* 0.46* 0.11 0.15 0.76* 0.89* 0.05 0.03 0.01 −0.01 0.03 0.00 
     Genistein 0.66* 0.76* 0.76* 0.89* 0.60* 0.71* 0.35* 0.39* 0.13 0.18 0.70* 0.79* 0.06 
     Glycitein 0.61* 0.68* 0.62* 0.68* 0.680.810.36* 0.33* 0.10 0.11 0.61* 0.66* 0.12 0.05 −0.07 −0.16 −0.02 −0.12 
     O-DMA 0.36* 0.47* 0.26* 0.34* 0.27* 0.36* 0.66* 0.82* 0.04 0.06 0.36* 0.45* −0.02 −0.01 −0.02 −0.01 0.00 0.02 
     Equol 0.11 0.18 0.16 0.24* 0.08 0.15 0.18 0.22* 0.620.810.17 0.24* −0.04 −0.01 0.02 0.06 0.01 0.06 
 Lignans −0.02 0.03 −0.13 −0.10 −0.11 −0.09 0.04 0.05 0.03 0.05 −0.06 −0.02 0.37* 0.47* 0.77* 0.91* 0.76* 0.93* 
     Enterodiol 0.05 0.08 0.00 0.03 0.04 0.08 −0.01 0.01 0.02 0.04 0.04 0.07 0.670.830.23* 0.28* 0.33* 0.40* 
     Enterolactone −0.03 −0.01 −0.15 −0.13 −0.13 −0.13 0.02 0.01 0.02 0.03 −0.08 −0.06 0.27* 0.34* 0.810.940.75* 0.90* 

Note: Pearson correlation coefficients on log-transformed data. Correlation coefficients between urine and serum levels are indicated in bold for particular phytoestrogens.

*P < 0.001.

P < 0.05.

P < 0.01.

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