Multivariable-adjusteda relative risk [95% confidence interval (CI)] of breast cancer diagnosed anytime after baseline according to quintiles of energy-adjusted glycemic load stratified by physical activity and by menopausal status and physical activity simultaneously
| . | No. of cases . | Quintile of glycemic load . | . | . | . | . | P for trend . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | . | 1 . | 2 . | 3 . | 4 . | 5 . | . | |||||||
| All women, by tertile kJ expended in physical activity | ||||||||||||||
| Lowest tertile physical activity | 311 | 1.00 | 1.25 (0.88–1.78) | 1.12 (0.75–1.66) | 1.14 (0.74–1.75) | 1.24 (0.75–2.04) | 0.53 | |||||||
| Middle tertile physical activity | 305 | 1.00 | 0.92 (0.63–1.34) | 0.70 (0.46–1.07) | 0.84 (0.54–1.29) | 1.00 (0.61–1.65) | >0.99 | |||||||
| Highest tertile physical activity | 281 | 1.00 | 0.72 (0.47–1.09) | 0.98 (0.65–1.46) | 0.74 (0.47–1.16) | 0.77 (0.46–1.29) | 0.39 | |||||||
| Premenopausal women, by tertile kJ expended in physical activity | ||||||||||||||
| Lowest tertile physical activity | 119 | 1.00 | 1.60 (0.91–2.84) | 1.52 (0.79–2.91) | 1.62 (0.79–3.34) | 2.35 (1.03–5.37) | 0.07 | |||||||
| Middle tertile physical activity | 120 | 1.00 | 0.93 (0.50–1.72) | 0.77 (0.39–1.54) | 1.02 (0.50–2.09) | 1.48 (0.66–3.33) | 0.28 | |||||||
| Highest tertile physical activity | 99 | 1.00 | 0.35 (0.17–0.71) | 0.67 (0.36–1.27) | 0.61 (0.31–1.23) | 0.49 (0.21–1.16) | 0.22 | |||||||
| Postmenopausal women, by tertile kJ expended in physical activity | ||||||||||||||
| Lowest tertile physical activity | 192 | 1.00 | 1.07 (0.68–1.69) | 0.93 (0.56–1.54) | 0.91 (0.53–1.56) | 0.84 (0.45–1.57) | 0.50 | |||||||
| Middle tertile physical activity | 185 | 1.00 | 0.93 (0.58–1.50) | 0.69 (0.40–1.17) | 0.75 (0.43–1.30) | 0.79 (0.42–1.51) | 0.40 | |||||||
| Highest tertile physical activity | 182 | 1.00 | 1.18 (0.68–2.05) | 1.41 (0.81–2.44) | 0.95 (0.51–1.75) | 1.12 (0.57–2.21) | 0.97 | |||||||
| . | No. of cases . | Quintile of glycemic load . | . | . | . | . | P for trend . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | . | 1 . | 2 . | 3 . | 4 . | 5 . | . | |||||||
| All women, by tertile kJ expended in physical activity | ||||||||||||||
| Lowest tertile physical activity | 311 | 1.00 | 1.25 (0.88–1.78) | 1.12 (0.75–1.66) | 1.14 (0.74–1.75) | 1.24 (0.75–2.04) | 0.53 | |||||||
| Middle tertile physical activity | 305 | 1.00 | 0.92 (0.63–1.34) | 0.70 (0.46–1.07) | 0.84 (0.54–1.29) | 1.00 (0.61–1.65) | >0.99 | |||||||
| Highest tertile physical activity | 281 | 1.00 | 0.72 (0.47–1.09) | 0.98 (0.65–1.46) | 0.74 (0.47–1.16) | 0.77 (0.46–1.29) | 0.39 | |||||||
| Premenopausal women, by tertile kJ expended in physical activity | ||||||||||||||
| Lowest tertile physical activity | 119 | 1.00 | 1.60 (0.91–2.84) | 1.52 (0.79–2.91) | 1.62 (0.79–3.34) | 2.35 (1.03–5.37) | 0.07 | |||||||
| Middle tertile physical activity | 120 | 1.00 | 0.93 (0.50–1.72) | 0.77 (0.39–1.54) | 1.02 (0.50–2.09) | 1.48 (0.66–3.33) | 0.28 | |||||||
| Highest tertile physical activity | 99 | 1.00 | 0.35 (0.17–0.71) | 0.67 (0.36–1.27) | 0.61 (0.31–1.23) | 0.49 (0.21–1.16) | 0.22 | |||||||
| Postmenopausal women, by tertile kJ expended in physical activity | ||||||||||||||
| Lowest tertile physical activity | 192 | 1.00 | 1.07 (0.68–1.69) | 0.93 (0.56–1.54) | 0.91 (0.53–1.56) | 0.84 (0.45–1.57) | 0.50 | |||||||
| Middle tertile physical activity | 185 | 1.00 | 0.93 (0.58–1.50) | 0.69 (0.40–1.17) | 0.75 (0.43–1.30) | 0.79 (0.42–1.51) | 0.40 | |||||||
| Highest tertile physical activity | 182 | 1.00 | 1.18 (0.68–2.05) | 1.41 (0.81–2.44) | 0.95 (0.51–1.75) | 1.12 (0.57–2.21) | 0.97 | |||||||
Multivariable model was adjusted for age, body mass index, alcohol, smoking, age at menarche, age at first pregnancy, number of pregnancies, oral contraceptive use, postmenopausal hormone use, family history of breast cancer, physical activity, total energy, energy-adjusted total fat, energy-adjusted total fiber, and energy-adjusted folate.