American Association for Cancer Research

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Table 1

Mean ± SD of baseline characteristics of the 191 study subjects by the VDR FokI genotype

Variable	VDR FokI genotype					P ^a
Variable		FF	Ff	ff		P ^a
No. of subjects (%)	78 (41%)	73 (38%)	40 (21%)
Age at surgery (yrs)	64.8 ± 6.8	65.2 ± 6.5	63.2 ± 6.2	0.28
% Gleason grade 4/5	42.8 ± 30.0	43.8 ± 30.2	30.3 ± 28.6	0.05^b
Index cancer volume (cc)	5.2 ± 5.3	5.3 ± 5.7	5.7 ± 6.0	0.88
Preoperative serum PSA (ng/ml)	24.5 ± 39.5	19.7 ± 23.2	18.5 ± 14.1	0.49

Variable	VDR FokI genotype					P ^a
Variable		FF	Ff	ff		P ^a
No. of subjects (%)	78 (41%)	73 (38%)	40 (21%)
Age at surgery (yrs)	64.8 ± 6.8	65.2 ± 6.5	63.2 ± 6.2	0.28
% Gleason grade 4/5	42.8 ± 30.0	43.8 ± 30.2	30.3 ± 28.6	0.05^b
Index cancer volume (cc)	5.2 ± 5.3	5.3 ± 5.7	5.7 ± 6.0	0.88
Preoperative serum PSA (ng/ml)	24.5 ± 39.5	19.7 ± 23.2	18.5 ± 14.1	0.49

^a

By ANOVA.

^b

P = 0.015 by t test when the FF and Ff genotypes were combined and compared with the ff genotype.