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Table 3

Stratification analysis of the XPA A23G genotype frequencies in cases and controls

XPA GG genotype
Cases (n = 265)Controls (n = 185)Crude OR (95% CI)Adjusted OR (95% CI)
No.Others%No.Others%
Age (yr)         
 ≤62 16 108 12.9 26 72 26.5 0.41 (0.21–0.82) 0.39 (0.19–0.80)ab 
 >62 29 112 20.6 20 67 23.0 0.87 (0.46–1.65) 0.76 (0.39–1.48)a 
Sex         
 Male 36 183 16.4 39 111 26.0 0.56 (0.34–0.93) 0.51 (0.30–0.86)bc 
 Female 37 19.6 28 20.0 0.97 (0.32–2.93) 0.82 (0.25–2.69)c 
Smoking status         
 Current 35 170 17.1 28 72 28.0 0.53 (0.30–0.93) 0.46 (0.25–0.83)bd 
 Former 11 21.4 29 21.6 0.99 (0.22–4.42) 0.91 (0.20–4.22)d 
 Never 39 15.2 10 38 20.8 0.68 (0.24–1.98) 0.69 (0.24–2.02)e 
Pack-yearsf         
 ≤30 13 73 15.1 20 59 25.3 0.53 (0.24–1.14) 0.48 (0.21–1.08)d 
 >30 25 108 18.8 16 42 27.6 0.61 (0.30–1.25) 0.58 (0.28–1.21)d 
XPA GG genotype
Cases (n = 265)Controls (n = 185)Crude OR (95% CI)Adjusted OR (95% CI)
No.Others%No.Others%
Age (yr)         
 ≤62 16 108 12.9 26 72 26.5 0.41 (0.21–0.82) 0.39 (0.19–0.80)ab 
 >62 29 112 20.6 20 67 23.0 0.87 (0.46–1.65) 0.76 (0.39–1.48)a 
Sex         
 Male 36 183 16.4 39 111 26.0 0.56 (0.34–0.93) 0.51 (0.30–0.86)bc 
 Female 37 19.6 28 20.0 0.97 (0.32–2.93) 0.82 (0.25–2.69)c 
Smoking status         
 Current 35 170 17.1 28 72 28.0 0.53 (0.30–0.93) 0.46 (0.25–0.83)bd 
 Former 11 21.4 29 21.6 0.99 (0.22–4.42) 0.91 (0.20–4.22)d 
 Never 39 15.2 10 38 20.8 0.68 (0.24–1.98) 0.69 (0.24–2.02)e 
Pack-yearsf         
 ≤30 13 73 15.1 20 59 25.3 0.53 (0.24–1.14) 0.48 (0.21–1.08)d 
 >30 25 108 18.8 16 42 27.6 0.61 (0.30–1.25) 0.58 (0.28–1.21)d 
a

Adjusted for sex and pack-years.

b

P = 0.01.

c

Adjusted for age and pack-years.

d

Adjusted for age, sex, and pack-years.

e

Adjusted for age and sex.

f

In current and former smoker.

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