American Association for Cancer Research

Table 4

Association of free testosterone with age, ethnicity, BMI, and waist circumference; regression coefficients (β)^a from Generalized Estimating Equations

Variable	Model 1^b			Model 2^b			Model 3^b
Variable		β (ng/ml)	P	β (ng/ml)	P	β (ng/ml)	P
Visit age, per yr	−0.0030	<0.0001	−0.0030	<0.0001	−0.0029	<0.0001
Black race	0.0035	0.18	0.0049	0.068	0.0033	0.23
Year 2 BMI, per 1 kg/m²			−0.0008	0.014	0.0005	0.47
Δ BMI, per 1 kg/m²			−0.0016	0.0046	−0.001	0.19
Year 2 waist circumference, per 1 cm					−0.0005	0.063
Δ Waist circumference, per 1 cm					−0.0002	0.32

Variable	Model 1^b			Model 2^b			Model 3^b
Variable		β (ng/ml)	P	β (ng/ml)	P	β (ng/ml)	P
Visit age, per yr	−0.0030	<0.0001	−0.0030	<0.0001	−0.0029	<0.0001
Black race	0.0035	0.18	0.0049	0.068	0.0033	0.23
Year 2 BMI, per 1 kg/m²			−0.0008	0.014	0.0005	0.47
Δ BMI, per 1 kg/m²			−0.0016	0.0046	−0.001	0.19
Year 2 waist circumference, per 1 cm					−0.0005	0.063
Δ Waist circumference, per 1 cm					−0.0002	0.32

Mean change in free testosterone corresponding to the indicated difference in the independent variable.

Each of the models also included terms for secular changes in hormone levels between the Year 2 and 7, and the Years 2 and 10 examinations.

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