American Association for Cancer Research

Skip to Main Content

Table 2.

CRC incidence trends among young (20-49 y) non-Hispanic Whites by sex, age, stage at diagnosis, and anatomic subsite, 1992 to 2005

			n	Line segment 1		Line segment 2
				Year	APC*	Year	APC*
Age	Men	20-29	249	1992-2005	5.2^†
		30-39	1,419	1992-2005	3.0^†
		40-49	5,080	1992-2005	1.5^†
	Women	20-29	240	1992-2005	5.6^†
		30-39	1,125	1992-2005	2.0^†
		40-49	4,261	1992-2005	2.1^†
Stage	Men	Local	2,345	1992-2005	2.5^†
		Regional	2,626	1992-2005	2.0^†
		Distant	1,554	1992-2005	1.8^†
		Unstaged	223	1992-2005	−3.1
	Women	Local	2,091	1992-2005	3.5^†
		Regional	2,139	1992-1995	−4.6	1995-2005	1.7
		Distant	1,266	1992-2005	3.7^†
		Unstaged	130	1992-2005	−4.0
Subsite	Men	Proximal colon	2,054	1992-2005	0.0
		Distal colon	1,609	1992-2005	1.5^†
		Rectum	2,609	1992-2005	3.5^†
	Women	Proximal colon	1,548	1992-2005	0.8
		Distal colon	1,619	1992-2005	2.3^†
		Rectum	2,065	1992-2005	2.9^†

			n	Line segment 1		Line segment 2
				Year	APC*	Year	APC*
Age	Men	20-29	249	1992-2005	5.2^†
		30-39	1,419	1992-2005	3.0^†
		40-49	5,080	1992-2005	1.5^†
	Women	20-29	240	1992-2005	5.6^†
		30-39	1,125	1992-2005	2.0^†
		40-49	4,261	1992-2005	2.1^†
Stage	Men	Local	2,345	1992-2005	2.5^†
		Regional	2,626	1992-2005	2.0^†
		Distant	1,554	1992-2005	1.8^†
		Unstaged	223	1992-2005	−3.1
	Women	Local	2,091	1992-2005	3.5^†
		Regional	2,139	1992-1995	−4.6	1995-2005	1.7
		Distant	1,266	1992-2005	3.7^†
		Unstaged	130	1992-2005	−4.0
Subsite	Men	Proximal colon	2,054	1992-2005	0.0
		Distal colon	1,609	1992-2005	1.5^†
		Rectum	2,609	1992-2005	3.5^†
	Women	Proximal colon	1,548	1992-2005	0.8
		Distal colon	1,619	1992-2005	2.3^†
		Rectum	2,065	1992-2005	2.9^†

NOTE: Trends were analyzed by Joinpoint Regression Program, Version 3.0, with a maximum of three joinpoints (i.e., four line segments).

APC based on incidence rates age-adjusted to the 2000 US standard population.

The APC is significantly different from zero (P < 0.05).